Lichen depsidones with biological interest

I Ureña-Vacas, E González-Burgos, PK Divakar… - Planta …, 2022 - thieme-connect.com
Depsidones are some of the most abundant secondary metabolites produced by lichens.
These compounds have aroused great pharmacological interest due to their activities as …

A comparative study of isolated secondary metabolites from lichens and their antioxidative properties

J Elečko, M Vilková, R Frenák, D Routray, D Ručová… - Plants, 2022 - mdpi.com
Free radicals play a critical role in the chemical processes that occur in all cells.
Pharmaceutical companies manufacture a variety of synthetically prepared antioxidants, but …

Thermodynamic and kinetic studies of the antiradical activity of 5-hydroxymethylfurfural: computational insights

H Boulebd, A Mechler, NT Hoa, QV Vo - New Journal of Chemistry, 2020 - pubs.rsc.org
5-Hydroxymethylfurfural (HMF) is a natural product derived from the degradation of sugars in
eg milk, honey and raisins. Recent studies have shown that this compound has several …

Recent advances on natural depsidones: Sources, biosynthesis, structure-activity relationship, and bioactivities

MT Khayat, KF Ghazawi, WA Samman, AA Alhaddad… - PeerJ, 2023 - peerj.com
Depsidones are a class of polyphenolic polyketides that have been proposed to be
biosynthesized from oxidative coupling of esters of two polyketidic benzoic acid derivatives …

Anti-Osteoclastogenic and Antibacterial Effects of Chlorinated Polyketides from the Beibu Gulf Coral-Derived Fungus Aspergillus unguis GXIMD 02505

Y Zhang, Z Li, B Huang, K Liu, S Peng, X Liu, C Gao… - Marine Drugs, 2022 - mdpi.com
One new depsidone derivative, aspergillusidone H (3), along with seven known
biosynthetically related chlorinated polyketides, were obtained from the Beibu Gulf coral …

Lichen extracts from Cetrarioid clade provide neuroprotection against hydrogen peroxide-induced oxidative stress

I Ureña-Vacas, E González-Burgos, PK Divakar… - Molecules, 2022 - mdpi.com
Oxidative stress is involved in the pathophysiology of many neurodegenerative diseases.
Lichens have antioxidant properties attributed to their own secondary metabolites with …

Feruloylmonotropeins: promising natural antioxidants in Paederia scandens

NQ Trung, NTT Thanh, NT Hoa, A Mechler, QV Vo - RSC advances, 2023 - pubs.rsc.org
Paederia scandens (Lour.) is a widely used medicinal herb in Vietnam, China, India, and
Japan for the treatment of a variety of conditions, including toothache, chest pains, piles, and …

[HTML][HTML] Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly

J Yang, Z Zhou, Y Chen, Y Song, J Ju - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Depsides and depsidones have attracted attention for biosynthetic studies due to their broad
biological activities and structural diversity. Previous structure‒activity relationships …

Antioxidant behavior affected by polarity in the olive oil: Experimental and molecular simulation investigations

J Tang, G You, L Ruan, Y Lu, B Wen, S Wu - ACS omega, 2021 - ACS Publications
Natural antioxidants are essential potential sources for protecting the oxidation of food oils.
However, until now, the mechanisms are still not very clear, especially from the quantitatively …

The scavenging mechanism of hydrazone compounds towards HOO˙ and CH 3 OO˙ radicals: a computational mechanistic and kinetic study

C Kaur, D Mandal - RSC Advances, 2025 - pubs.rsc.org
In this study, a detailed DFT investigation was conducted to systematically analyze the
scavenging activity of six hydrazone compounds (1–6) against HOO˙ and CH3OO˙ radicals …