Systemic sclerosis is a chronic autoimmune disease of still not fully understood
pathogenesis. Fibrosis, vascular wall damage, and disturbances of innate and acquired …

Background Data on survival and prognosis factors in incident cohorts are scarce in
systemic sclerosis (SStc). To describe survival, standardized mortality ratio (SMR), and …

Introduction: Primary heart involvement in systemic sclerosis may cause morpho-functional
and electrical cardiac abnormalities and is a common cause of death. The absence of a …

Scleroderma (systemic sclerosis) is an autoimmune rheumatic disorder that is characterized
by fibrosis, vascular dysfunction, and autoantibody production that involves most visceral …

Systemic sclerosis (SSc) is a rare and complex immune-mediated connective tissue disease
characterized by multi-organ fibrosis and dysfunction. Systemic sclerosis-associated …

Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is a catastrophic
complication of one of the most common and devastating autoimmune diseases. Once …

Abstract Background Systemic sclerosis (SSc) is associated with a variability of mortality
rates in the literature. Objective To determine the mortality and its predictors in a long-term …

Abstract Systemic Sclerosis (SSc) is an autoimmune disorder characterized by
microvascular injury and diffuse fibrosis of the skin and internal organs. While …

Background: Clinically evident primary heart involvement due to systemic sclerosis (SHI) is
considered a poor prognostic factor and is a leading cause of systemic sclerosis (SSc) …

Systemic sclerosis is an auto-immune disease characterized by skin involvement that often
affects multiple organ systems. Pulmonary hypertension is a common finding that can …