Mercury involvement in neuronal damage and in neurodegenerative diseases

VL Cariccio, A Samà, P Bramanti, E Mazzon - Biological trace element …, 2019 - Springer
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and multiple sclerosis are characterized by a chronic and …

Tolerogenic dendritic cells as a promising antigen-specific therapy in the treatment of multiple sclerosis and neuromyelitis optica from preclinical to clinical trials

G Flórez-Grau, I Zubizarreta, R Cabezón… - Frontiers in …, 2018 - frontiersin.org
The identification of activated T-lymphocytes restricted to myelin-derived immunogenic
peptides in multiple sclerosis (MS) and aquaporin-4 water channel in neuromyelitis optica …

New targets and therapeutics for neuroprotection, remyelination and repair in multiple sclerosis

P Villoslada, L Steinman - Expert opinion on investigational drugs, 2020 - Taylor & Francis
Introduction Immunotherapies for multiple sclerosis (MS) significantly decrease the risk of
new relapses. However, the chronic compartmentalized inflammation and …

Androgen therapy in neurodegenerative diseases

VE Bianchi, L Rizzi, E Bresciani… - Journal of the …, 2020 - academic.oup.com
Neurodegenerative diseases, including Alzheimer disease (AD), Parkinson disease (PD),
multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Huntington disease, are …

A robust clustering strategy for stratification unveils unique patient subgroups in acutely decompensated cirrhosis

S Palomino-Echeverria, E Huergo… - Journal of Translational …, 2024 - Springer
Background Patient heterogeneity poses significant challenges for managing individuals
and designing clinical trials, especially in complex diseases. Existing classifications rely on …

Visual evoked potentials to monitor myelin cuprizone-induced functional changes

S Marenna, SC Huang, G Dalla Costa, R d'Isa… - Frontiers in …, 2022 - frontiersin.org
The visual system is one of the most accessible routes to study the central nervous system
under pathological conditions, such as in multiple sclerosis (MS). Non-invasive visual …

Could mathematics be the key to unlocking the mysteries of multiple sclerosis?

G Weatherley, RP Araujo, SJ Dando… - Bulletin of Mathematical …, 2023 - Springer
Multiple sclerosis (MS) is an autoimmune, neurodegenerative disease that is driven by
immune system-mediated demyelination of nerve axons. While diseases such as cancer …

[HTML][HTML] Toxic heavy metal concentrations in multiple sclerosis patients: A systematic review and meta-analysis

S Sarihi, M Niknam, S Mahjour… - EXCLI …, 2021 - ncbi.nlm.nih.gov
The present meta-analysis was performed to assess the association between MS patients
and control subjects in terms of their circulating levels of arsenic (As), lead (Pb), mercury …

The potential of computational modeling to predict disease course and treatment response in patients with relapsing multiple sclerosis

F Pappalardo, G Russo, M Pennisi… - Cells, 2020 - mdpi.com
As of today, 20 disease-modifying drugs (DMDs) have been approved for the treatment of
relapsing multiple sclerosis (MS) and, based on their efficacy, they can be grouped into …

MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis

E Kotelnikova, NA Kiani, D Messinis… - Proceedings of the …, 2019 - National Acad Sciences
Dysregulation of signaling pathways in multiple sclerosis (MS) can be analyzed by
phosphoproteomics in peripheral blood mononuclear cells (PBMCs). We performed in vitro …