Pulmonary surfactant is a complex and highly surface active material composed of lipids and
proteins which is found in the fluid lining the alveolar surface of the lungs. Surfactant …

▪ Abstract SP-B is the only surfactant-associated protein absolutely required for postnatal
lung function and survival. Complete deficiency of SP-B in mice and humans results in …

Surfactant protein B (SP-B) is an 8.7-kDa, hydrophobic protein that enhances the spreading
and stability of surfactant phospholipids in the alveolus. To further assess the role of SP-B in …

Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Mutations in the genes encoding the surfactant proteins B and C (SP-B and SP-C) and the
phospholipid transporter, ABCA3, are associated with respiratory distress and interstitial …

This article starts with a brief account of the history of research on pulmonary surfactant. We
will then discuss the morphological aspects and composition of the pulmonary surfactant …

The extensive pulmonary alveolar and capillary networks make the lungs highly susceptible
to cell and tissue injury from pathogens or toxic environmental agents present either in the …

Interstitial lung disease (ILD) of unknown etiology in immunocompetent patients is rare in
children. A national survey was carried out in the United Kingdom and Ireland over a 3‐year …

▪ Abstract The hydrophobic surfactant proteins, SP-B and SP-C, have important roles in
surfactant function. The importance of these proteins in normal lung function is highlighted …

Pulmonary alveolar proteinosis (PAP) is a heterogeneous disorder of genetic or acquired
etiologies. In some cases congenital PAP is associated with hereditary surfactant protein …