The discovery of microRNAs (miRNAs), almost 10 years ago, changed dramatically our
perspective on eukaryotic gene expression regulation. However, the broad and important …

Hypoxia induces protective autophagy in glioblastoma cells and new therapeutic avenues
that target this process may improve the outcome for glioblastoma patients. Recent studies …

MicroRNAs (miRNAs) are a novel class of small noncoding RNA molecules that regulate
gene expression by inducing degradation or translational inhibition of target mRNAs. There …

Growing recognition of the numerous, diverse and important roles played by non-coding
RNA in all organisms motivates better elucidation of these cellular components …

MicroRNAs (miRNAs) are short regulatory RNAs that inhibit target genes by complementary
binding in 3′ untranslated regions (3′ UTRs). They are one of the most abundant classes …

Motivation: Clustering according to sequence–structure similarity has now become a
generally accepted scheme for ncRNA annotation. Its application to complete genomic …

Trypanosoma brucei has three distinct∼ 20S editosomes that catalyze RNA editing by the
insertion and deletion of uridylates. Editosomes with the KREN1 or KREN2 RNase III type …

An ensemble classifier approach for microRNA precursor (pre-miRNA) classification was
proposed based upon combining a set of heterogeneous algorithms including support …

Liverworts are the most basal group of extant land plants. Nonetheless, the molecular
biology of liverworts is poorly understood. Gene expression has been studied in only one …

Mirtrons are intronic hairpin substrates of the dicing machinery that generate functional
microRNAs. In this study, we describe experimental assays that defined the essential …