Epithelial–mesenchymal transition (EMT) is a reversible cellular process, characterized by
changes in gene expression and activation of proteins, favoring the trans-differentiation of …

Signaling by the extracellular signal-regulated kinase (ERK) pathway controls many cellular
processes, including cell division, death, and differentiation. In this second installment of a …

Background Our previous study showed Musashi2 (MSI2) promoted chemotherapy
resistance and pernicious biology of pancreatic cancer (PC) by down-regulating Numb and …

MicroRNAs (miRNAs) have been validated to play prominent roles in the occurrence and
development of bladder cancer (BCa). MiR-22 was previously reported to act as a tumor …

Background Clear cell renal cell carcinoma (ccRCC) is a major worldwide health problem
due to its high prevalence and mortality rate. A disintegrin and metalloproteinase 12 …

Epithelial to mesenchymal transition (EMT) is the process whereby a polarized epithelial cell
ceases to maintain cell-cell contacts, loses expression of characteristic epithelial cell …

Background Our previous study showed that calreticulin (CRT) promoted EGF-induced
epithelial-mesenchymal transition (EMT) in pancreatic cancer (PC) via Integrin/EGFR …

The mammalian skull vault is a highly regulated structure that evolutionally protects brain
growth during vertebrate development. It consists of several membrane bones with different …

Abstract Purpose miR-410-3p plays opposite roles in different cancers and may act as an
oncomiR or tumor suppressor miR. The purpose of this study was to assess the role of miR …

ABSTRACT FAM172A, as a newly discovered gene, is little known in cancer development,
especially in pancreatic cancer (PC). We investigated the potential role and molecular …