[HTML][HTML] DeepConsensus improves the accuracy of sequences with a gap-aware sequence transformer

G Baid, DE Cook, K Shafin, T Yun… - Nature …, 2023 - nature.com
Circular consensus sequencing with Pacific Biosciences (PacBio) technology generates
long (10–25 kilobases), accurate 'HiFi'reads by combining serial observations of a DNA …

In it for the long run: perspectives on exploiting long-read sequencing in livestock for population scale studies of structural variants

TV Nguyen, CJ Vander Jagt, J Wang… - Genetics Selection …, 2023 - Springer
Studies have demonstrated that structural variants (SV) play a substantial role in the
evolution of species and have an impact on Mendelian traits in the genome. However, unlike …

[HTML][HTML] Diversity of ribosomes at the level of rRNA variation associated with human health and disease

D Rothschild, TT Susanto, X Sui, JP Spence, R Rangan… - Cell Genomics, 2024 - cell.com
With hundreds of copies of rDNA, it is unknown whether they possess sequence variations
that form different types of ribosomes. Here, we developed an algorithm for long-read variant …

BugSplit enables genome-resolved metagenomics through highly accurate taxonomic binning of metagenomic assemblies

I Chandrakumar, NPG Gauthier, C Nelson… - Communications …, 2022 - nature.com
A large gap remains between sequencing a microbial community and characterizing all of
the organisms inside of it. Here we develop a novel method to taxonomically bin …

Atlas of telomeric repeat diversity in Arabidopsis thaliana

Y Tao, W Xian, Z Bao, FA Rabanal, A Movilli, C Lanz… - Genome Biology, 2024 - Springer
Background Telomeric repeat arrays at the ends of chromosomes are highly dynamic in
composition, but their repetitive nature and technological limitations have made it difficult to …

BugSplit: highly accurate taxonomic binning of metagenomic assemblies enables genome-resolved metagenomics

I Chandrakumar, NPG Gauthier, C Nelson, MB Bonsall… - bioRxiv, 2021 - biorxiv.org
A large gap remains between sequencing a microbial community and characterizing all of
the organisms inside of it. Here we develop a novel method to taxonomically bin …

[PDF][PDF] Diversity of ribosomes at the level of rRNA variation associated with human health and

D Rothschild, TT Susanto, X Sui, JP Spence, R Rangan… - jeffspence.github.io
With hundreds of copies of ribosomal DNA (rDNA) it is unknown whether they possess
sequence variations that ultimately form different types of ribosomes. Here, we developed an …

[PDF][PDF] Analysis and assembly methods for microbiome sequencing data

MW Fedarko - interpretation - fedarko.github.io
Recent and frequent advances in DNA sequencing technologies and algorithms have
enabled the study of microbiomes, populations of microorganisms in environments ranging …

[图书][B] Accurate Genome Analysis with Nanopore Sequencing Using Deep Neural Networks

K Shafin - 2022 - search.proquest.com
Nanopore sequencing, commercialized by Oxford Nanopore Technology (ONT), is a high-
throughput genome sequencing platform. Unlike traditional sequencing-by-synthesis …