Hyponatremia is a common water balance disorder that often poses a diagnostic or
therapeutic challenge. Therefore, guidelines were developed by professional organizations …

Hyponatremia is a serious, but often overlooked, electrolyte imbalance that has been
independently associated with a wide range of deleterious changes involving many different …

Human cells dwell in salt water. Their well-being depends on the ability of the body to
regulate the salinity of extracellular fluids. By controlling water intake and excretion, the …

Hyponatremia is the most common electrolyte disorder, affecting more than 15% of patients
in the hospital. Syndrome of inappropriate antidiuresis (SIAD) is the most frequent cause of …

Patients with severe (serum sodium≤ 120 mEq/L), symptomatic hyponatremia can develop
life-threatening or fatal complications from cerebral edema if treatment is inadequate and …

Background Osmotic demyelination syndrome (ODS) is a rare but potentially devastating
neurologic complication of hyponatremia. The primary objective of this study was to identify …

International guidelines designed to minimize the risk of complications that can occur when
correcting severe hyponatremia have been widely accepted for a decade. On the basis of …

Hyponatremia is defined by low serum sodium concentration and is the most common
electrolyte disorder encountered in clinical practice. Serum sodium is the main determinant …

Results Mean age was 66 years old (SD= 15), 55% were women, and 67% had prior
hyponatremia (last outpatient sodium< 135 mEq/L). Median change in serum sodium at 24 …

Abstract Treatment of hypotonic hyponatremia often challenges clinicians on many counts.
Despite similar serum sodium concentrations, clinical manifestations can range from mild to …