Betulin and its derivatives as novel compounds with different pharmacological effects

S Amiri, S Dastghaib, M Ahmadi, P Mehrbod… - Biotechnology …, 2020 - Elsevier
Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …

Triterpenes as potentially cytotoxic compounds

M Chudzik, I Korzonek-Szlacheta, W Król - Molecules, 2015 - mdpi.com
Triterpenes are compounds of natural origin, which have numerously biological activities:
anti-cancer properties, anti-inflammatory, anti-oxidative, anti-viral, anti-bacterial and anti …

Antibacterial and antioxidant activities of ursolic acid and derivatives

PGG Do Nascimento, TLG Lemos, AMC Bizerra… - Molecules, 2014 - mdpi.com
Ursolic acid, an important bioactive compound, was isolated from ethanol extract of aerial
parts of Sambucus australis. In order to develop bioactive ursolic acid derivatives, two semi …

Ursolic acid derivatives for pharmaceutical use: a patent review (2012-2016)

H Hussain, IR Green, I Ali, IA Khan, Z Ali… - Expert Opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Ursolic acid (UA), belongs to a group of pentacyclic triterpenoids
and is known to possess some very interesting biological properties. Protocols have been …

Phytochemistry, chemotaxonomy, ethnopharmacology, and nutraceutics of Lamiaceae

C Frezza, A Venditti, M Serafini, A Bianco - Studies in natural products …, 2019 - Elsevier
Lamiaceae (or Labiatae) is a family of plants included in the Angiosperms group comprising
12 subfamilies, 16 tribes, 9 subtribes, 236 genera, and more than 7000 species. It …

Triterpenes with healing activity: A systematic review

LC Agra, JNS Ferro, FT Barbosa… - Journal of Dermatological …, 2015 - Taylor & Francis
The purpose of this review was to systematically evaluate the literature on the efficacy of
triterpenes for wound healing. We searched for original studies in the Medline, SCIDIRECT …

Differential metabolomic fingerprinting of the crude extracts of three Asteraceae species with assessment of their in vitro antioxidant and enzyme-inhibitory activities …

G Zengin, NM Fahmy, KI Sinan, AI Uba, A Bouyahya… - Processes, 2022 - mdpi.com
The Asteraceae is a large family, rich in ornamental, economical, and medicinally valuable
plants. The current study involves the analytical and pharmacological assessment of the …

Mechanistic approach of anti-diabetic compounds identified from natural sources

R Dabur, B Sharma, A Mittal - Chemical Biology Letters, 2018 - pubs.iscience.in
Abstract Type-2 diabetes mellitus (T2DM) is a global disease, which leads to various other
life threatening diseases and affects the quality of life. Current therapies of T2DM have …

Anti-cancer and anti-angiogenic properties of various natural pentacyclic tri-terpenoids and some of their chemical derivatives

EE Rufino-Palomares, A Perez-Jimenez… - Current Organic …, 2015 - benthamdirect.com
Pentacyclic triterpenes are natural substances, synthesized and present in variable amounts
in a large number of terrestrial and aquatic plants, which act not only as antioxidants and …

Influence of terpene type on the release from an O/W nanoemulsion: Experimental and theoretical studies

M Miastkowska, P Śliwa - Molecules, 2020 - mdpi.com
The interaction between a drug molecule and its carrier's components is an important factor
which influences the drug release profile. For this purpose, molecular dynamics (MD) may …