Obesity and diabetes—Not only a simple link between two epidemics

A Chobot, K Górowska‐Kowolik… - Diabetes/metabolism …, 2018 - Wiley Online Library
Diabetes (DM) as well as obesity, due to their increasing incidence, were recognized as
epidemic by the World Health Organization. Obesity is involved not only in the …

A review of insulin resistance in type 1 diabetes: is there a place for adjunctive metformin?

G Priya, S Kalra - Diabetes Therapy, 2018 - Springer
There is a rising trend of overweight and obesity among individuals with type 1 diabetes.
This is often associated with insulin resistance, increased insulin dose requirements and …

The time is right for a new classification system for diabetes: rationale and implications of the β-cell–centric classification schema

SS Schwartz, S Epstein, BE Corkey, SFA Grant… - Diabetes …, 2016 - Am Diabetes Assoc
The current classification system presents challenges to the diagnosis and treatment of
patients with diabetes mellitus (DM), in part due to its conflicting and confounding definitions …

DPP‐4 inhibitors as treatments for type 1 diabetes mellitus: a systematic review and meta‐analysis

Q Wang, M Long, H Qu, R Shen… - Journal of diabetes …, 2018 - Wiley Online Library
Objective. Several clinical studies have reported the application of dipeptidyl peptidase‐4
(DPP‐4) inhibitors as treatments for type 1 diabetes mellitus (T1DM). This study aims to …

Resveratrol improves glycemic control in insulin-treated diabetic rats: participation of the hepatic territory

CY Yonamine, E Pinheiro-Machado, ML Michalani… - Nutrition & …, 2016 - Springer
Background Resveratrol is a natural polyphenol that has been proposed to improve
glycemic control in diabetes, by mechanisms that involve improvement in insulin secretion …

Sodium–glucose cotransporter inhibitors as add‐on therapy in addition to insulin for type 1 diabetes mellitus: A meta‐analysis of randomized controlled trials

H Zou, L Liu, J Guo, H Wang, S Liu… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction Several clinical trials reported the effects of sodium–glucose
cotransporter (SGLT) inhibitors in type 1 diabetes patients. This meta‐analysis aimed to …

Prescribing patterns of adjunctive therapy for the treatment of type 1 diabetes mellitus among Australian endocrinologists

P Forner, J Snaith, JR Greenfield - Internal Medicine Journal, 2024 - Wiley Online Library
Background Many people living with type 1 diabetes (type 1 diabetes mellitus (T1DM)) do
not meet glycaemic targets. Adjunctive therapies have both risks and metabolic benefits and …

Type 1 diabetes: key drug targets and how they could influence future therapeutics

YK Kim, KM Munir, SN Davis - Expert Opinion on Therapeutic …, 2023 - Taylor & Francis
Introduction Despite significant strides made in the management of T1DM, standard
management is still insulin analog therapy. Some non-insulin therapies traditionally …

Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes

SK Juin, S Pushpakumar, SC Tyagi, U Sen - Scientific Reports, 2022 - nature.com
Diabetic nephropathy is characterized by excessive accumulation of extracellular matrix
(ECM) leading to renal fibrosis, progressive deterioration of renal function, and eventually to …

Beyond type 2 diabetes: sodium glucose co‐transporter‐inhibition in type 1 diabetes

T Biester, O Kordonouri, T Danne - Diabetes, Obesity and …, 2019 - Wiley Online Library
Use of sodium glucose cotransporter (SGLT) inhibitors are a well‐established therapeutic
option in type 2 diabetes (T2D) with a variety of proven therapeutic benefits. They have …