Corroles at work: A small macrocycle for great applications
C Di Natale, CP Gros, R Paolesse - Chemical Society Reviews, 2022 - pubs.rsc.org
Corrole chemistry has witnessed an impressive boost in studies in the last 20 years, thanks
to the possibility of preparing corrole derivatives by simple synthetic procedures. The …
to the possibility of preparing corrole derivatives by simple synthetic procedures. The …
[HTML][HTML] Mouse models of colorectal cancer: Past, present and future perspectives
F Bürtin, CS Mullins, M Linnebacher - World journal of …, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common diagnosed malignancy among both
sexes in the United States as well as in the European Union. While the incidence and …
sexes in the United States as well as in the European Union. While the incidence and …
[HTML][HTML] LOX-1 and cancer: an indissoluble liaison
M Murdocca, C De Masi, S Pucci, R Mango… - Cancer gene …, 2021 - nature.com
Recently, a strong correlation between metabolic disorders, tumor onset, and progression
has been demonstrated, directing new therapeutic strategies on metabolic targets. OLR1 …
has been demonstrated, directing new therapeutic strategies on metabolic targets. OLR1 …
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1): a crucial driver of atherosclerotic cardiovascular disease
A Akhmedov, T Sawamura, CH Chen… - European heart …, 2021 - academic.oup.com
Cardiovascular diseases (CVDs), specifically lipid-driven atherosclerotic CVDs, remain the
number one cause of death worldwide. The lectin-like oxidized low-density lipoprotein (LDL) …
number one cause of death worldwide. The lectin-like oxidized low-density lipoprotein (LDL) …
Targeting the tumor microenvironment in colorectal peritoneal metastases
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC)
patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the …
patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the …
[HTML][HTML] Involvement of LDL and ox-LDL in cancer development and its therapeutical potential
CF Deng, N Zhu, TJ Zhao, HF Li, J Gu, DF Liao… - Frontiers in …, 2022 - frontiersin.org
Lipid metabolism disorder is related to an increased risk of tumorigenesis and is involved in
the rapid growth of cancer cells as well as the formation of metastatic lesions …
the rapid growth of cancer cells as well as the formation of metastatic lesions …
[HTML][HTML] Machine learning phenomics (MLP) combining deep learning with time-lapse-microscopy for monitoring colorectal adenocarcinoma cells gene expression …
High-throughput phenotyping is becoming increasingly available thanks to analytical and
bioinformatics approaches that enable the use of very high-dimensional data and to the …
bioinformatics approaches that enable the use of very high-dimensional data and to the …
[HTML][HTML] The role of C-type lectin receptor signaling in the intestinal microbiota-inflammation-cancer axis
M Li, R Zhang, J Li, J Li - Frontiers in Immunology, 2022 - frontiersin.org
As a subset of pattern recognition receptors (PRRs), C-type lectin-like receptors (CLRs) are
mainly expressed by myeloid cells as both transmembrane and soluble forms. CLRs …
mainly expressed by myeloid cells as both transmembrane and soluble forms. CLRs …
[HTML][HTML] Knockdown of OLR1 weakens glycolytic metabolism to repress colon cancer cell proliferation and chemoresistance by downregulating SULT2B1 via c-MYC
T Zhao, Y Li, K Shen, Q Wang, J Zhang - Cell death & disease, 2021 - nature.com
Chemoresistance is one of the major problems of colon cancer treatment. In tumors,
glycolytic metabolism has been identified to promote cell proliferation and chemoresistance …
glycolytic metabolism has been identified to promote cell proliferation and chemoresistance …
The oxidized‐LDL/LOX‐1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells
T Tsumita, N Maishi, DAM Annan… - … journal of cancer, 2022 - Wiley Online Library
Epidemiological relationships between cancer and cardiovascular diseases have been
reported, but a molecular basis remains unclear. Some proteoglycans that strongly bind low …
reported, but a molecular basis remains unclear. Some proteoglycans that strongly bind low …