[HTML][HTML] Adult neurogenesis in the mammalian brain: significant answers and significant questions
Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
important role for adult hippocampal neurogenesis in learning and memory, but its specific …
Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor
GZ Wei, KA Martin, PY Xing… - Proceedings of the …, 2021 - National Acad Sciences
While modulatory effects of gut microbes on neurological phenotypes have been reported,
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …
the mechanisms remain largely unknown. Here, we demonstrate that indole, a tryptophan …
Mitochondrial dysfunction in depression
Y Bansal, A Kuhad - Current neuropharmacology, 2016 - ingentaconnect.com
Background: Depression is the most debilitating neuropsychiatric disorder with significant
impact on socio-occupational and well being of individual. The exact pathophysiology of …
impact on socio-occupational and well being of individual. The exact pathophysiology of …
[HTML][HTML] N, N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca, regulates adult neurogenesis in vitro and in vivo
JA Morales-Garcia, J Calleja-Conde… - Translational …, 2020 - nature.com
Abstract N, N-dimethyltryptamine (DMT) is a component of the ayahuasca brew traditionally
used for ritual and therapeutic purposes across several South American countries. Here, we …
used for ritual and therapeutic purposes across several South American countries. Here, we …
Functions and dysfunctions of adult hippocampal neurogenesis
Adult neurogenesis, a developmental process of generating functionally integrated neurons,
occurs throughout life in the hippocampus of the mammalian brain and showcases the …
occurs throughout life in the hippocampus of the mammalian brain and showcases the …
Adult hippocampal neurogenesis in depression
The development of new treatments for depression is predicated upon identification of
neural substrates and mechanisms that underlie its etiology and pathophysiology. The …
neural substrates and mechanisms that underlie its etiology and pathophysiology. The …
Emerging roles of Wnts in the adult nervous system
NC Inestrosa, E Arenas - Nature Reviews Neuroscience, 2010 - nature.com
The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …
Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …
modulated transcription factor that governs the expression of genes involved in …
[HTML][HTML] A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain
Active adult neurogenesis occurs in discrete brain regions of all mammals and is widely
regarded as a neuronal replacement mechanism. Whether adult-born neurons make unique …
regarded as a neuronal replacement mechanism. Whether adult-born neurons make unique …