Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
[HTML][HTML] The amoeboid state as part of the epithelial-to-mesenchymal transition programme
V Graziani, I Rodriguez-Hernandez, O Maiques… - Trends in cell …, 2022 - cell.com
Cell migration is essential for many biological processes, while abnormal cell migration is
characteristic of cancer cells. Epithelial cells become motile by undergoing epithelial-to …
characteristic of cancer cells. Epithelial cells become motile by undergoing epithelial-to …
Effects of polystyrene microplastics on human kidney and liver cell morphology, cellular proliferation, and metabolism
KE Goodman, T Hua, QXA Sang - ACS omega, 2022 - ACS Publications
Microplastics have gained much attention due to their prevalence and abundance in our
everyday lives. They have been detected in household items such as sugar, salt, honey …
everyday lives. They have been detected in household items such as sugar, salt, honey …
Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair
LL Scheffer, SC Sreetama, N Sharma… - Nature …, 2014 - nature.com
In muscle and other mechanically active tissue, cell membranes are constantly injured, and
their repair depends on the injury-induced increase in cytosolic calcium. Here, we show that …
their repair depends on the injury-induced increase in cytosolic calcium. Here, we show that …
Emerging roles for lipids in non-apoptotic cell death
Non-apoptotic regulated cell death (RCD) is essential to maintain organismal homeostasis
and may be aberrantly activated during certain pathological states. Lipids are emerging as …
and may be aberrantly activated during certain pathological states. Lipids are emerging as …
Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans
Eosinophils release their granule proteins extracellularly through exocytosis, piecemeal
degranulation, or cytolytic degranulation. Findings in diverse human eosinophilic diseases …
degranulation, or cytolytic degranulation. Findings in diverse human eosinophilic diseases …
Inherent P2X7 receptors regulate macrophage functions during inflammatory diseases
W Ren, P Rubini, Y Tang, T Engel, P Illes - International Journal of …, 2021 - mdpi.com
Macrophages are mononuclear phagocytes which derive either from blood-borne
monocytes or reside as resident macrophages in peripheral (Kupffer cells of the liver …
monocytes or reside as resident macrophages in peripheral (Kupffer cells of the liver …
Listeriolysin O: the Swiss army knife of Listeria
MA Hamon, D Ribet, F Stavru, P Cossart - Trends in microbiology, 2012 - cell.com
Listeriolysin O (LLO) is a toxin produced by Listeria monocytogenes, an opportunistic
bacterial pathogen responsible for the disease listeriosis. This disease starts with the …
bacterial pathogen responsible for the disease listeriosis. This disease starts with the …
[HTML][HTML] Ultrasound-mediated drug delivery: sonoporation mechanisms, biophysics, and critical factors
CH YuAlfred - BME frontiers, 2022 - spj.science.org
Sonoporation, or the use of ultrasound in the presence of cavitation nuclei to induce plasma
membrane perforation, is well considered as an emerging physical approach to facilitate the …
membrane perforation, is well considered as an emerging physical approach to facilitate the …
S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells
JK Jaiswal, SP Lauritzen, L Scheffer… - Nature …, 2014 - nature.com
Cell migration and invasion require increased plasma membrane dynamics and ability to
navigate through dense stroma, thereby exposing plasma membrane to tremendous …
navigate through dense stroma, thereby exposing plasma membrane to tremendous …