Metabolic associated fatty liver disease (MAFLD) is one of the most common causes of
chronic liver disease worldwide. To date, there is no FDA-approved treatment, so there is an …

Ovarian damage and fertility impairment are major side effects of chemotherapy in pre-
menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present …

Liver fibrosis is a liver disease in which there is an excessive buildup of extracellular matrix
proteins, including collagen. By regulating cytokine production and the inflammatory …

Abstract 3, 3′, 4′, 4′, 5-Polychlorinated biphenyls (PCB126) is classified as a persistent
organic environmental pollutant that can cause liver damage by producing excessive …

Cholestatic liver disease is characterized by disturbances in the intestinal microbiota and
excessive accumulation of toxic bile acids (BA) in the liver. Melatonin (MT) can improve liver …

Background Hepatotoxicity associated with methotrexate (MTX) is mainly due to disruption
of redox balance and development of oxidative injury to hepatocytes. Melatonin (MLT) is a …

Liver fibrosis is a chronic progressive disease, its resolution still unclear, and the current
study explored the role of melatonin in modulation of interleukin-6 (IL-6), interleukin-4 (IL-4) …

Oxidative damage is associated to numerous diseases as well as aging development.
Mitochondria found in most eukaryotic organisms to create the energy of the cell, generate …

ABSTRACT Tyrosinemia type 1 (TT1) is caused by fumarylacetoacetate hydrolase activity
deficiency, resulting in tissue accumulation of upstream metabolites, including …

Анотація Патологія ендокринних органів може призводити до печінкової дисфункції та,
навпаки, захворювання печінки можуть спричинити порушення ендокринної функції. В …