ROS-1 Fusions in Non-Small-Cell Lung Cancer: Evidence to Date

S Gendarme, O Bylicki, C Chouaid, F Guisier - Current oncology, 2022 - mdpi.com
The ROS-1 gene plays a major role in the oncogenesis of numerous tumors. ROS-1
rearrangement is found in 0.9–2.6% of non-small-cell lung cancers (NSCLCs), mostly lung …

Targeting ALK rearrangements in NSCLC: current state of the art

L Peng, L Zhu, Y Sun, J Stebbing, G Selvaggi… - Frontiers in …, 2022 - frontiersin.org
Anaplastic lymphoma kinase (ALK) alterations in non-small cell lung cancer (NSCLC) can
be effectively treated with a variety of ALK-targeted drugs. After the approval of the first …

[HTML][HTML] Low-dose computed tomography (LDCT) lung cancer screening in Asian female never-smokers is as efficacious in detecting lung cancer as in Asian male …

N Triphuridet, SS Zhang, M Nagasaka, Y Gao… - Journal of Thoracic …, 2023 - Elsevier
Introduction Lung cancer in never-smokers is the major cancer cause of death globally. We
compared the efficacy of low-dose computed tomography (LDCT) lung cancer screening …

Unmet needs, quality of life, and financial toxicity among survivors of lung cancer

ML Hsu, MC Boulanger, S Olson, C Eaton… - JAMA Network …, 2024 - jamanetwork.com
Importance Despite a growing population of survivors of lung cancer, there is limited
understanding of the survivorship journey. Survivors of lung cancer experience unmet …

Therapeutical options in ROS1—rearranged advanced non small cell lung cancer

B Stanzione, A Del Conte, E Bertoli, E De Carlo… - International Journal of …, 2023 - mdpi.com
ROS proto-oncogene 1 (ROS1) rearrangements occur in 0.9–2.6% of patients with non
small cell lung cancer (NSCLC), conferring sensitivity to treatment with specific tyrosine …

Derivation, validation and assessment of a novel nomogram-based risk assessment model for venous thromboembolism in hospitalized patients with lung cancer: a …

H Li, Y Tian, H Niu, L He, G Cao, C Zhang… - Frontiers in …, 2022 - frontiersin.org
Purpose This study aimed to develop and validate a specific risk-stratification nomogram
model for the prediction of venous thromboembolism (VTE) in hospitalized patients with lung …

From Development to Place in Therapy of Lorlatinib for the Treatment of ALK and ROS1 Rearranged Non-Small Cell Lung Cancer (NSCLC)

L Fabbri, A Di Federico, M Astore, V Marchiori… - Diagnostics, 2023 - mdpi.com
Following the results of the CROWN phase III trial, the third-generation macrocyclic ALK
inhibitor lorlatinib has been introduced as a salvage option after the failure of a first-line TKI …

Lung Cancer Related Thrombosis (LCART): Focus on Immune Checkpoint Blockade

A Charpidou, G Gerotziafas, S Popat, A Araujo… - Cancers, 2024 - mdpi.com
Simple Summary Thrombotic events are a common problem for lung cancer patients.
Compared to other types of cancer, lung cancer patients are more likely to experience blood …

The Role of EGFR Amplification in Deep Venous Thrombosis Occurrence in IDH Wild-Type Glioblastoma

B Kaye, A Ali, RA Correa Bastianon Santiago… - Current …, 2023 - mdpi.com
Introduction: Glioblastoma (GBM) patients have a 20–30 incidence of venous
thromboembolic events. EGFR is a widely used prognostic marker for many cancers. Recent …

Progress of non-small-cell lung cancer with ROS1 rearrangement

X Yang, Z Tang, J Li, J Jiang, Y Liu - Frontiers in Molecular …, 2023 - frontiersin.org
ROS1 rearrangement is found in 0.9%–2.6% of people with non-small-cell lung cancers
(NSCLCs). Tyrosine kinase inhibitors (TKIs) target ROS1 and can block tumor growth and …