Current and novel biomarkers of thrombotic risk in COVID-19: a consensus statement from the international COVID-19 thrombosis biomarkers colloquium

DA Gorog, RF Storey, PA Gurbel, US Tantry… - Nature Reviews …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and
thromboembolic events, owing to excessive inflammation, endothelial cell activation and …

Tissue factor in COVID-19-associated coagulopathy

S Subramaniam, H Kothari, M Bosmann - Thrombosis Research, 2022 - Elsevier
Evidence of micro-and macro-thrombi in the arteries and veins of critically ill COVID-19
patients and in autopsies highlight the occurrence of COVID-19-associated coagulopathy …

Persistent endotheliopathy in the pathogenesis of long COVID syndrome

H Fogarty, L Townsend, H Morrin… - … of thrombosis and …, 2021 - Wiley Online Library
Background Persistent symptoms including breathlessness, fatigue, and decreased exercise
tolerance have been reported in patients after acute SARS‐CoV‐2 infection. The biological …

[HTML][HTML] The ADAMTS13‐von Willebrand factor axis in COVID‐19 patients

I Mancini, L Baronciani, A Artoni, P Colpani… - Journal of Thrombosis …, 2021 - Elsevier
Background Severe coronavirus disease 2019 (COVID‐19) is characterized by an increased
risk of thromboembolic events, with evidence of microthrombosis in the lungs of deceased …

ADAMTS13 regulation of VWF multimer distribution in severe COVID‐19

SE Ward, H Fogarty, E Karampini… - … of Thrombosis and …, 2021 - Wiley Online Library
Background Consistent with fulminant endothelial cell activation, elevated plasma von
Willebrand factor (VWF) antigen levels have been reported in patients with COVID‐19. The …

COVID‐19–related laboratory coagulation findings

KMJ Devreese - International journal of laboratory hematology, 2021 - Wiley Online Library
The alterations in the hemostatic balance in COVID‐19 patients are strongly disturbed and
contribute to a high prothrombotic status. The high rate of venous thromboembolism in …

Thrombin generation in patients with COVID-19 with and without thromboprophylaxis

E Campello, C Bulato, L Spiezia, A Boscolo… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Thrombin generation (TG) with and without thrombomodulin (TM) was evaluated
in COVID-19 patients with different disease severity and thromboprophylaxis regimen, in …

COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alternative complement pathway under cytokine storm

Y Fujimura, LZ Holland - International Journal of Hematology, 2022 - Springer
ADAMTS13, a metalloproteinase, specifically cleaves unusually large multimers of von
Willebrand factor (VWF), newly released from vascular endothelial cells. The ratio of …

[HTML][HTML] The relationship between COVID-19 infection and intracranial hemorrhage: a systematic review

SR Daly, AV Nguyen, Y Zhang, D Feng, JH Huang - Brain Hemorrhages, 2021 - Elsevier
Introduction In addition to the deleterious effects Covid-19 has on the pulmonary and
cardiovascular systems, COVID-19 can also result in damage to the nervous system. This …

[HTML][HTML] Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA Interdisciplinary Expert Consensus

C Buske, M Dreyling, A Alvarez-Larrán, J Apperley… - ESMO open, 2022 - Elsevier
Background The COVID-19 pandemic has created enormous challenges for the clinical
management of patients with hematological malignancies (HMs), raising questions about …