[HTML][HTML] Dietary antioxidants and Parkinson's disease

HA Park, AC Ellis - Antioxidants, 2020 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder caused by the depletion of
dopaminergic neurons in the basal ganglia, the movement center of the brain …

[HTML][HTML] Pre-Clinical studies identifying molecular pathways of neuroinflammation in Parkinson's disease: a systematic review

M Fathi, K Vakili, S Yaghoobpoor… - Frontiers in Aging …, 2022 - frontiersin.org
Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by neuroinflammation, formation of Lewy bodies, and progressive loss of …

The neuroprotective role of MiR‐124‐3p in a 6‐hydroxydopamine‐induced cell model of Parkinson's disease via the regulation of ANAX5

RF Dong, B Zhang, LW Tai, HM Liu… - Journal of Cellular …, 2018 - Wiley Online Library
ABSTRACT Parkinson's disease (PD), the second most common neurodegenerative
disorder, is characterized by a progressive loss of dopaminergic neurons in the midbrain …

[HTML][HTML] Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis

Z Yin, X Geng, Z Zhang, Y Wang, X Gao - Frontiers in Pharmacology, 2021 - frontiersin.org
Neuronal mitochondrial oxidative stress induced by β-amyloid (Aβ) is an early event of
Alzheimer's disease (AD). Emerging evidence has shown that antioxidant therapy …

Characterization of Electrospun Polysuccinimide‐Dopamine Conjugates and Effect on Cell Viability and Uptake

K Tóth, K S. Nagy, Z Güler, ÁG Juhász… - Macromolecular …, 2023 - Wiley Online Library
Biocompatible nanofibrous systems made by electrospinning have been studied widely for
pharmaceutical applications since they have a high specific surface and the capability to …

Mimicking Parkinson's disease in a dish: merits and pitfalls of the most commonly used dopaminergic in vitro models

FM Lopes, IJ Bristot, LL Da Motta, RB Parsons… - NeuroMolecular …, 2017 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disorder and has
both unknown etiology and non-curative therapeutic options. Patients begin to present the …

From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease

TPC Chierrito, S Pedersoli-Mantoani, C Roca… - European Journal of …, 2017 - Elsevier
The lack of an effective treatment for Alzheimer'disease (AD), an increasing prevalence and
severe neurodegenerative pathology boost medicinal chemists to look for new drugs …

Influence of serum concentration in retinoic acid and phorbol ester induced differentiation of SH-SY5Y human neuroblastoma cell line

KB Magalingam, AK Radhakrishnan… - Molecular Biology …, 2020 - Springer
Numerous protocols to establish dopaminergic phenotype in SH-SY5Y cells have been
reported. In most of these protocols there are variations in concentration of serum used. In …

The effects of neuronal cell differentiation on TRPM7, TRPM8 and TRPV1 channels in the model of Parkinson's disease

A Öz, Ö Çelik - Neurological research, 2022 - Taylor & Francis
ABSTRACT Transient Receptor Potential Melastatin-like 7 (TRPM7), Transient Receptor
Potential Melastatin-like 8 (TRPM8) and Transient Receptor Potential Vanilloid-like 1 …

Downregulation of TRPM7, TRPM8, and TRPV1 channels modulate apoptotic parameters and neurodegenerative markers: Focus on neuronal differentiation and …

A Öz, Ö Çelik - Cell biology international, 2023 - Wiley Online Library
The transient receptor potential channel (TRP) channels are expressed in neuronal tissues
and involved in neurological diseases such as pain, epilepsy, neuronal apoptosis, and …