The hand endows us with unparalleled precision and versatility in our interactions with
objects, from mundane activities such as grasping to extraordinary ones such as virtuoso …

Stroke instigates a dynamic process of repair and remodelling of remaining neural circuits,
and this process is shaped by behavioural experiences. The onset of motor disability …

An account of the neurobiology of motor recovery in the arm and hand after stroke by two
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …

Highlights•Convergence between axon regeneration ability and abnormal synaptic structure
and function.•Axon regeneration, neuronal circuit assembly and recovery of functions in the …

The motor cortex is far from a stable conduit for motor commands and instead undergoes
significant changes during learning. An understanding of motor cortex plasticity has been …

Injury due to stroke and traumatic brain injury result in significant long‐term effects upon
behavioral functioning. One central question to rehabilitation research is whether the nature …

Central nervous system (CNS) injuries, including stroke, traumatic brain injury, and spinal
cord injury, are leading causes of long-term disability. It is estimated that more than half of …

Although motor deficits in humans with diabetic neuropathy have been extensively
researched, its effect on the motor system is thought to be lesser than that on the sensory …

Motor recovery following ischemic stroke is contingent on the ability of surviving brain
networks to compensate for damaged tissue. In rodent models, sensory and motor cortical …

Intensive rehabilitation is believed to induce use-dependent plasticity in the injured nervous
system; however, its causal relationship to functional recovery is unclear. Here, we …