Degradable biomedical elastomers (DBE), characterized by controlled biodegradability,
excellent biocompatibility, tailored elasticity, and favorable network design and …

Differentiating between two highly similar C–H bonds in a given molecule remains a
fundamental challenge in synthetic organic chemistry. Directing group assisted strategies for …

Selective oxidation of the γ-C–H bonds from abundant amine feedstocks via palladium
catalysis is a valuable transformation in synthesis and medicinal chemistry. Despite …

While chain‐walking stimulates wide interest in both polymerization and organic synthesis,
site‐and stereoselective control of chain‐walking on rings is still a challenging task in the …

α, β-Dehydrogenation of aliphatic acids has been realized through both enolate and β-C–H
metalation pathways. However, the synthesis of isolated β, γ-unsaturated aliphatic acids via …

Herein, the density functional theory method was employed to investigate the mechanism of
the ligand-promoted divergent α, β-dehydrogenation of aliphatic acids. The calculated …

Dehydrogenation of an alkyl group via C–H activation forms a vinyl unit, which can act as a
versatile stepping stone for diverse late-stage structural modifications at two adjacent sp 3 …

The progress of efficient and sustainable approaches for decarboxylative coupling reactions
is synthetically appealing due to the structural diversity, lack of toxicity, and widespread …

In this report, we present a photopromoted, metal-free transannulation of phenyl azides for
the synthesis of DNA-encoded seven-membered rings. The transformation is efficiently …

Abstract γ‐methylene C (sp3)− H functionalization of linear free carboxylic acids remains a
significant challenge. Here in we report a Pd (II)‐catalyzed tandem γ‐arylation and γ …