Treating metastatic cancer with nanotechnology

A Schroeder, DA Heller, MM Winslow… - Nature Reviews …, 2012 - nature.com
Metastasis accounts for the vast majority of cancer deaths. The unique challenges for
treating metastases include their small size, high multiplicity and dispersion to diverse organ …

Synthesis, functionalization, and design of magnetic nanoparticles for theranostic applications

J Mosayebi, M Kiyasatfar… - Advanced Healthcare …, 2017 - Wiley Online Library
In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs)
have been presented as a class of non‐invasive nanomaterials for numerous biomedical …

Cancer theranostics: the rise of targeted magnetic nanoparticles

AJ Cole, VC Yang, AE David - Trends in biotechnology, 2011 - cell.com
Interest in utilizing magnetic nanoparticles (MNP) for biomedical applications has increased
considerably over the past two decades. This excitement has been driven in large part by …

Nanomaterials for neural interfaces

NA Kotov, JO Winter, IP Clements, E Jan… - Advanced …, 2009 - Wiley Online Library
This review focuses on the application of nanomaterials for neural interfacing. The junction
between nanotechnology and neural tissues can be particularly worthy of scientific attention …

EGFRvIII antibody–conjugated iron oxide nanoparticles for magnetic resonance imaging–guided convection-enhanced delivery and targeted therapy of glioblastoma

CG Hadjipanayis, R Machaidze, M Kaluzova, L Wang… - Cancer research, 2010 - AACR
The magnetic nanoparticle has emerged as a potential multifunctional clinical tool that can
provide cancer cell detection by magnetic resonance imaging (MRI) contrast enhancement …

Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain

HL Liu, MY Hua, HW Yang, CY Huang… - Proceedings of the …, 2010 - National Acad Sciences
The superparamagnetic properties of magnetic nanoparticles (MNPs) allow them to be
guided by an externally positioned magnet and also provide contrast for MRI. However, their …

Magnetic drug targeting: preclinical in vivo studies, mathematical modeling, and extrapolation to humans

KT Al-Jamal, J Bai, JTW Wang, A Protti, P Southern… - Nano …, 2016 - ACS Publications
A sound theoretical rationale for the design of a magnetic nanocarrier capable of magnetic
capture in vivo after intravenous administration could help elucidate the parameters …

Magnetic Nanoparticle-Based Approaches to Locally Target Therapy and Enhance Tissue Regeneration In Vivo

R Sensenig, Y Sapir, C MacDonald, S Cohen… - …, 2012 - Taylor & Francis
Magnetic-based systems utilizing superparamagnetic nanoparticles and a magnetic field
gradient to exert a force on these particles have been used in a wide range of biomedical …

SPIO-conjugated, doxorubicin-loaded microbubbles for concurrent MRI and focused-ultrasound enhanced brain-tumor drug delivery

CH Fan, CY Ting, HJ Lin, CH Wang, HL Liu, TC Yen… - Biomaterials, 2013 - Elsevier
The blood–brain barrier (BBB) can be temporarily and locally opened by focused ultrasound
(FUS) in the presence of circulating microbubbles (MBs). Currently, contrast-enhanced …

Biodistribution and targeting properties of iron oxide nanoparticles for treatments of cancer and iron anemia disease

E Alphandéry - Nanotoxicology, 2019 - Taylor & Francis
IONP (iron oxide nanoparticles) commercialized for treatments of iron anemia or cancer
diseases can be administered at doses exceeding 1 g per patient, indicating their bio …