Diagnosis and treatment of Merkel cell carcinoma: European consensus-based interdisciplinary guideline–Update 2022
ML Gauci, C Aristei, JC Becker, A Blom… - European Journal of …, 2022 - Elsevier
Merkel cell carcinoma (MCC) is a rare skin cancer, accounting for less than 1% of all
cutaneous malignancies. It is found predominantly in white populations and risk factors …
cutaneous malignancies. It is found predominantly in white populations and risk factors …
Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
neuroendocrine features. MCC pathogenesis is associated with either the presence of …
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …
advanced age and immunosuppression. Over the past decade, an association has been …
Molecular pathogenesis of Merkel cell carcinoma
JA DeCaprio - Annual Review of Pathology: Mechanisms of …, 2021 - annualreviews.org
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin with
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …
Biology and evolution of poorly differentiated neuroendocrine tumors
Neuroendocrine (NE) cancers are a diverse group of neoplasms typically diagnosed and
treated on the basis of their site of origin. This Perspective focuses on advances in our …
treated on the basis of their site of origin. This Perspective focuses on advances in our …
Merkel cell polyomavirus and Merkel cell carcinoma
V Pietropaolo, C Prezioso, U Moens - Cancers, 2020 - mdpi.com
Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …
Biology, evolution, and medical importance of polyomaviruses: An update
U Moens, A Krumbholz, B Ehlers, R Zell… - Infection, Genetics and …, 2017 - Elsevier
The family Polyomaviridae encompasses non-enveloped viruses with a circular dsDNA
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …
Are there multiple cells of origin of Merkel cell carcinoma?
Merkel cell carcinoma (MCC) is a rare but lethal cancer with the highest case-by-case fatality
rate among all skin cancers. Eighty percent of cancers are associated with the Merkel cell …
rate among all skin cancers. Eighty percent of cancers are associated with the Merkel cell …
Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis
Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell
polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small …
polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small …
Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC
Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer. Its
carcinogenesis may be either caused by the clonal integration of the Merkel cell …
carcinogenesis may be either caused by the clonal integration of the Merkel cell …