A comprehensive review on chlorpyrifos toxicity with special reference to endocrine disruption: Evidence of mechanisms, exposures and mitigation strategies

HU ur Rahman, W Asghar, W Nazir, MA Sandhu… - Science of The Total …, 2021 - Elsevier
Chlorpyrifos (CPF) is a broad-spectrum chlorinated organophosphate (OP) pesticide used
for the control of a variety of insects and pathogens in crops, fruits, vegetables, as well as …

Chlorpyrifos occurrence and toxicological risk assessment: a review

E Wołejko, B Łozowicka, A Jabłońska-Trypuć… - International journal of …, 2022 - mdpi.com
Chlorpyrifos (CPF) was the most frequently used pesticide in food production in the
European Union (EU) until 2020. Unfortunately, this compound is still being applied in other …

Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound/metabolite levels, and primary DNA …

N Kopjar, S Žunec, G Mendaš, V Micek… - Chemico-Biological …, 2018 - Elsevier
In this 28 day-study, we evaluated the effects of the insecticide chlorpyrifos orally
administered to Wistar rats at doses 0.160, 0.015, and 0.010 mg/kg bw/day. Following …

Statement on the available outcomes of the human health assessment in the context of the pesticides peer review of the active substance chlorpyrifos

European Food Safety Authority (EFSA) - EFSA Journal, 2019 - Wiley Online Library
Abstract In July 2019, the European Commission asked EFSA to provide a statement on the
available outcomes of the human health assessment in the context of the pesticides peer …

Short-term and persistent impacts on behaviors related to locomotion, anxiety, and startle responses of Japanese medaka (Oryzias latipes) induced by acute …

X Qiu, S Nomichi, K Chen, M Honda, IJ Kang… - Aquatic Toxicology, 2017 - Elsevier
Although most exposures to chlorpyrifos (CPF) in natural flowing waters are brief and
episodic, there have been a few reports of the persistence of abnormal fish behaviors …

Cytotoxic, genotoxic and biochemical markers of insecticide toxicity evaluated in human peripheral blood lymphocytes and an HepG2 cell line

D Želježić, M Mladinić, S Žunec, AL Vrdoljak… - Food and chemical …, 2016 - Elsevier
This study evaluated the cyto-and genotoxic effects of three pesticides: α-cypermethrin,
chlorpyrifos and imidacloprid applied in vitro to human lymphocytes and HepG2 cells for …

Histopathological and genotoxic effects of chlorpyrifos in rats

L Ezzi, I Belhadj Salah, Z Haouas, A Sakly… - … Science and Pollution …, 2016 - Springer
This study aims to investigate the effects of chlorpyrifos's sub-acute exposure on male rats.
Two groups with six animals each were orally treated, respectively, with 3.1 mg/kg bw and …

Enantioselective degradation of the organophosphorus insecticide isocarbophos in Cupriavidus nantongensis X1T: Characteristics, enantioselective regulation …

L Fang, L Xu, N Zhang, Q Shi, T Shi, X Ma, X Wu… - Journal of Hazardous …, 2021 - Elsevier
The chiral pesticide enantiomers often show selective efficacy and non-target toxicity. In this
study, the enantioselective degradation characteristics of the chiral organophosphorus …

Modulation of immune response by organophosphate pesticides: Mammals as potential model

A Mitra, M Sarkar, C Chatterjee - Proceedings of the Zoological Society, 2019 - Springer
Organophosphates (OPs) are most widely used pesticides and primarily induce toxicity by
inhibition of acetylcholinesterase (AChE) in the nerve terminals of central and peripheral …

Chromosome Missegregation and Aneuploidy Induction in Human Peripheral Blood Lymphocytes In vitro by Low Concentrations of Chlorpyrifos, Imidacloprid and α …

V Mužinić, S Ramić, D Želježić - Environmental and molecular …, 2019 - Wiley Online Library
Chlorpyrifos, imidacloprid, and α‐cypermethrin are some of the most widely used
insecticides in contemporary agriculture. However, their low‐dose, nontarget genotoxic …