New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
[HTML][HTML] Retinopathy of prematurity: A review of pathophysiology and signaling pathways
M Fevereiro-Martins, C Marques-Neves… - survey of …, 2023 - Elsevier
Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the retina and a leading
cause of visual impairment and childhood blindness worldwide. The disease is …
cause of visual impairment and childhood blindness worldwide. The disease is …
[HTML][HTML] Organ-organ communication: The liver's perspective
Communication between organs participates in most physiological and pathological events.
Owing to the importance of precise coordination among the liver and virtually all organs in …
Owing to the importance of precise coordination among the liver and virtually all organs in …
Dyslipidemia in retinal metabolic disorders
The light‐sensitive photoreceptors in the retina are extremely metabolically demanding and
have the highest density of mitochondria of any cell in the body. Both physiological and …
have the highest density of mitochondria of any cell in the body. Both physiological and …
Retinopathy of prematurity: Metabolic risk factors
At preterm birth, the retina is incompletely vascularized. Retinopathy of prematurity (ROP) is
initiated by the postnatal suppression of physiological retinal vascular development that …
initiated by the postnatal suppression of physiological retinal vascular development that …
Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity
A Salminen, K Kaarniranta, A Kauppinen - Cellular signalling, 2017 - Elsevier
FGF21 is a multifunctional metabolic and stress hormone which is normally expressed in
liver but cellular stress, eg mitochondrial or endoplasmic reticulum (ER) stress, can induce …
liver but cellular stress, eg mitochondrial or endoplasmic reticulum (ER) stress, can induce …
[HTML][HTML] Determining the role of SGLT2 inhibition with dapagliflozin in the development of diabetic retinopathy
LY Herat, JR Matthews, WE Ong… - Frontiers in Bioscience …, 2022 - imrpress.com
Background: Diabetic retinopathy (DR) is a major cause of blindness globally. Sodium
Glucose Cotransporter-2 (SGLT2) inhibitors have been demonstrated to exert cardiorenal …
Glucose Cotransporter-2 (SGLT2) inhibitors have been demonstrated to exert cardiorenal …
Insights into the liver-eyes connections, from epidemiological, mechanical studies to clinical translation
J Wu, C Duan, Y Yang, Z Wang, C Tan, C Han… - Journal of Translational …, 2023 - Springer
Maintenance of internal homeostasis is a sophisticated process, during which almost all
organs get involved. Liver plays a central role in metabolism and involves in endocrine …
organs get involved. Liver plays a central role in metabolism and involves in endocrine …
Pemafibrate protects against retinal dysfunction in a murine model of diabetic retinopathy
Diabetic retinopathy (DR) is one of the leading causes of blindness globally. Retinal
neuronal abnormalities occur in the early stage in DR. Therefore, maintaining retinal …
neuronal abnormalities occur in the early stage in DR. Therefore, maintaining retinal …
Beyond the liver: Liver-eye communication in clinical and experimental aspects
TH Yuan, ZS Yue, GH Zhang, L Wang… - Frontiers in Molecular …, 2021 - frontiersin.org
The communication between organs participates in the regulation of body homeostasis
under physiological conditions and the progression and adaptation of diseases under …
under physiological conditions and the progression and adaptation of diseases under …