The Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause
important diseases in humans. These include Trypanosoma brucei (the causative agent of …

In many eukaryotes, phospholipids (PLs) and sphingolipids (SLs) are abundant membrane
components and reservoirs for important signaling molecules. In Leishmania, the …

Protozoan parasites of the genus Leishmania undergo a complex life cycle involving
transmission by biting sand flies and replication within mammalian macrophage …

Carbohydrate Chemistry and Glycobiology have witnessed a rapid expansion during the last
few years with the development of numerous new, imaginative and efficient syntheses which …

We have tested the suitability of the green fluorescent protein (GFP) of Aequorea victoria as
a marker for studies of gene expression and protein targeting in the trypanosomatid parasite …

Leishmania are intracellular protozoan parasites that reside primarily in host mononuclear
phagocytes. Infection of host macrophages is initiated by infective promastigote stages and …

A key feature of many pathogenic microorganisms is the presence of a dense glycocalyx at
their surface, composed of lipid-anchored glycoproteins and non-protein-bound …

Proteophosphoglycans are an expanding family of highly glycosylated Leishmania proteins
with many unusual and some unique structural features. The novel protein–glycan linkage in …

In physiological conditions, both β-amyloid precursor protein (βAPP) and cellular prion (PrP
c) undergo similar disintegrin-mediated α-secretase cleavage yielding N-terminal secreted …

Many eukaryotic cell surface proteins are bound to the membrane via the
glycosylphosphatidylinositol (GPI) anchor that is covalently linked to their carboxy‐terminus …