Possibilities and challenges for developing a successful vaccine for leishmaniasis
Leishmaniasis is a vector-borne disease caused by different species of protozoan parasites
of the genus Leishmania. It is a major health problem yet neglected tropical diseases, with …
of the genus Leishmania. It is a major health problem yet neglected tropical diseases, with …
Vaccines for visceral leishmaniasis: A review
K Jain, NK Jain - Journal of immunological methods, 2015 - Elsevier
Visceral leishmaniasis, which is also known as Kala-Azar, is one of the most severely
neglected tropical diseases recognized by the World Health Organization (WHO). The threat …
neglected tropical diseases recognized by the World Health Organization (WHO). The threat …
Vaccine candidates for leishmaniasis: a review
R Nagill, S Kaur - International immunopharmacology, 2011 - Elsevier
Leishmaniasis is a diverse group of clinical syndromes caused by protozoan parasites of the
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …
genus Leishmania. The clinical manifestation of the disease varies from self-limiting …
[HTML][HTML] Vaccination in leishmaniasis: a review article
L Abdellahi, F Iraji, A Mahmoudabadi… - Iranian Biomedical …, 2022 - ncbi.nlm.nih.gov
Leishmaniasis is caused by protozoan Leishmania parasites that are transmitted through
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …
female sandfly bites. The disease is predominantly endemic to the tropics and semi-tropics …
[HTML][HTML] Old World cutaneous leishmaniasis: diagnosis and treatment
A Masmoudi, W Hariz, S Marrekchi… - Journal of …, 2013 - ncbi.nlm.nih.gov
Cutaneous leishmaniasis is a major world health problem. Diagnosis is suspected on
evocative clinical presentation in patients living in or coming from endemic areas. Several …
evocative clinical presentation in patients living in or coming from endemic areas. Several …
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani …
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
Development of vaccines against visceral leishmaniasis
KJ Evans, L Kedzierski - Journal of tropical medicine, 2012 - Wiley Online Library
Leishmaniasis is a neglected disease resulting in a global morbidity of 2,090 thousand
Disability‐Adjusted Life Years and a mortality rate of approximately 60,000 per year. Among …
Disability‐Adjusted Life Years and a mortality rate of approximately 60,000 per year. Among …
Optimized subunit vaccine protects against experimental leishmaniasis
S Bertholet, Y Goto, L Carter, A Bhatia, RF Howard… - Vaccine, 2009 - Elsevier
Development of a protective subunit vaccine against Leishmania spp. depends on antigens
and adjuvants that induce appropriate immune responses. We evaluated a second …
and adjuvants that induce appropriate immune responses. We evaluated a second …
Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis
MC Duarte, DP Lage, VT Martins… - Revista da Sociedade …, 2016 - SciELO Brasil
Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide.
Although chemotherapy has been widely used to treat this disease, problems related to the …
Although chemotherapy has been widely used to treat this disease, problems related to the …
Chimeric vaccines designed by immunoinformatics-activated polyfunctional and memory T cells that trigger protection against experimental visceral leishmaniasis
RCF De Brito, JC Ruiz, JMO Cardoso, TLVDP Ostolin… - Vaccines, 2020 - mdpi.com
Many vaccine candidates against visceral leishmaniasis (VL) have been proposed;
however, to date, none of them have been efficacious for the human or canine disease. On …
however, to date, none of them have been efficacious for the human or canine disease. On …