Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids

AW Schmidt, KR Reddy, HJ Knölker - Chemical reviews, 2012 - ACS Publications
Since our previous review, 1 there has been a tremendous development in the field of
carbazole alkaloids. New synthetic methodologies have been developed, existing …

Chemistry and properties of indolocarbazoles

T Janosik, A Rannug, U Rannug, N Wahlström… - Chemical …, 2018 - ACS Publications
The indolocarbazoles are an important class of nitrogen heterocycles which has evolved
significantly in recent years, with numerous studies focusing on their diverse biological …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

M Ishikura, K Yamada - Natural Product Reports, 2009 - pubs.rsc.org
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit - Natural Product
Reports (RSC Publishing) DOI:10.1039/B820693G Royal Society of Chemistry View PDF …

Recent progress in the chemistry and applications of indolocarbazoles

T Janosik, N Wahlström, J Bergman - Tetrahedron, 2008 - Elsevier
The indolocarbazoles constitute a family of condensed heterocyclic compounds featuring an
indole unit fused to one of the benzenoid rings of a carbazole moiety. Five isomers are …

Advances in the chemistry of natural and semisynthetic topoisomerase I/II inhibitors

VA D'yakonov, LU Dzhemileva… - Studies in natural products …, 2017 - Elsevier
The search for new, effective, and low-toxic anticancer agents is one of the most important
tasks of modern medicinal chemistry. In general, the solution to this problem comes down to …

Total syntheses of arcyriaflavin A and calothrixin B using 2, 2′-bisindole-3-acetic acid derivative as a common intermediate

S Lee, KH Kim, CH Cheon - Organic letters, 2017 - ACS Publications
A new protocol for the synthesis of 2, 2′-bisindole-3-acetic acid derivatives from aldimines
derived from 2-aminocinnamic acid derivatives and indole-2-carboxaldehyde was …

Total synthesis of calothrixin A and B via C–H activation

N Ramkumar, R Nagarajan - The Journal of Organic Chemistry, 2013 - ACS Publications
Total Synthesis of Calothrixin A and B via C–H Activation | The Journal of Organic
Chemistry ACS ACS Publications C&EN CAS Find my institution Log In The Journal of …

Synthesis of the Azepinobisindole Alkaloid Iheyamine A Enabled by a Cross-Mannich Reaction

AC Lindsay, IKH Leung, J Sperry - Organic letters, 2016 - ACS Publications
The total synthesis of the azepinobisindole alkaloid iheyamine A is described. The
successful strategy hinged on an intermolecular cross-Mannich reaction between 5-methoxy …

Concise total synthesis of calothrixins A and B

T Abe, T Ikeda, R Yanada, M Ishikura - Organic Letters, 2011 - ACS Publications
The concise total synthesis of calothrixins A and B has been accomplished by utilizing the
one-pot formation of hexatriene as a key intermediate via the palladium-catalyzed tandem …

N-Substituted calothrixin B derivatives inhibited the proliferation of HL-60 promyelocytic leukemia cells

N Hatae, R Satoh, H Chiba, T Osaki… - Medicinal Chemistry …, 2014 - Springer
Calothrixin B, whose structure consists of a pentacyclic indolo [3, 2-j] phenanthridine
framework, was originally isolated as a secondary metabolite from Calothrix cyanobacteria …