Novel approaches to diagnosis and management of hereditary transthyretin amyloidosis

A Carroll, PJ Dyck, M de Carvalho… - Journal of Neurology …, 2022 - jnnp.bmj.com
Hereditary transthyretin amyloidosis (ATTRv) is a severe, adult-onset autosomal dominant
inherited systemic disease predominantly affecting the peripheral and autonomic nervous …

Targeted therapies in pediatric and adult patients with hypertrophic heart disease: from molecular pathophysiology to personalized medicine

E Monda, A Bakalakos, M Rubino, F Verrillo… - Circulation: Heart …, 2023 - Am Heart Assoc
Hypertrophic cardiomyopathy is a myocardial disease defined by an increased left
ventricular wall thickness not solely explained by abnormal loading conditions. It is often …

A review of cardiac amyloidosis: presentation, diagnosis, and treatment

I Pour-Ghaz, A Bath, S Kayali, D Alkhatib… - Current Problems in …, 2022 - Elsevier
Amyloidosis is a group of disorders that can affect almost any organ due to the misfolding of
proteins with their subsequent deposition in various tissues, leading to various disease …

Diflunisal targeted delivery systems: A review

P Snetkov, S Morozkina, R Olekhnovich… - Materials, 2021 - mdpi.com
Diflunisal is a well-known drug for the treatment of rheumatoid arthritis, osteoarthritis,
primary dysmenorrhea, and colon cancer. This molecule belongs to the group of …

Changing paradigm in the treatment of amyloidosis: from disease-modifying drugs to anti-fibril therapy

CC Quarta, M Fontana, T Damy, J Catini… - Frontiers in …, 2022 - frontiersin.org
Cardiac amyloidosis is a rare, debilitating, and usually fatal disease increasingly recognized
in clinical practice despite patients presenting with non-specific symptoms of …

Current Evidence Supporting the Role of Immune Response in ATTRv Amyloidosis

D Plantone, G Primiano, D Righi, A Romano, M Luigetti… - Cells, 2023 - mdpi.com
Hereditary transthyretin (ATTRv) amyloidosis with polyneuropathy, also known as familial
amyloid polyneuropathy (FAP), represents a progressive, heterogeneous, severe, and …

Updates for the diagnosis and management of cardiac amyloidosis

P Gosciniak, T Baron, S Milczarek… - Advances in Clinical …, 2022 - diva-portal.org
A substantial increase in the interest in transthyretin cardiac amyloidosis (ATTR-CA) is a
result of the constantly growing number of patients, the use of clear diagnostic protocols and …

Cardiac Amyloidosis: A Contemporary Review of Medical and Surgical Therapy

D Brownell, AJ Pillai, N Nair - Current Cardiology Reviews, 2024 - ingentaconnect.com
Amyloidosis is a systemic disease initiated by deposition of misfolded proteins in the
extracellular space, due to which multiple organs may be affected concomitantly. Cardiac …

Dapagliflozin treatment and cardiovascular outcome in RBP4/TTRVal30Met (transthyretin cardiac amyloidosis) mice

Z Li, F Lv, X Wen, C Guo, L Li, X Cai, C Lin… - ESC Heart …, 2024 - Wiley Online Library
Aims Whether sodium‐glucose co‐transporter 2 inhibitors are effective for heart failure
caused by ATTR‐CA (transthyretin cardiac amyloidosis) remains uncertain. The aim of this …

[HTML][HTML] Temporal trends in diagnostic testing patterns for wild-type transthyretin amyloid cardiomyopathy in the medicare fee-for-service population

JM Bourque, A Schepart, R Bhambri, A Castaño… - The American Journal of …, 2022 - Elsevier
Wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM) is frequently misdiagnosed or
diagnosed late in the disease course. ATTRwt-CM can be diagnosed invasively through …