Introduction: Coumarins are a group of plant-derived polyphenolic compounds. They belong
to the benzopyrones family and possess a wide variety of cytoprotective and modulatory …

Advanced medullary thyroid cancers (MTCs) are now being treated with drugs that inhibit
receptor tyrosine kinases, many of which involved in angiogenesis. Response rates vary …

In recent years, transition metal-catalyzed strong C–C bond activation has significantly
attracted the attention of synthetic chemists. This protocol enables simultaneous and direct …

During this study, the in vitro antifungal and antibacterial activities of different extracts
(aqueous and organic) obtained from a French propolis batch were evaluated. Antifungal …

Melanoma is the most aggressive skin cancer, and its incidence has continued to rise during
the past decades. Conventional treatments present severe side effects in cancer patients …

Three new flavonoids,(2 R, 3 R)-3, 5-dihydroxy-7-methoxyflavanone 3-(2-methyl) butyrate
(1),(7′′ R)-8-[1-(4′-hydroxy-3′-methoxyphenyl) prop-2-en-1-yl] chrysin (2), and (7 …

Aims CYP53A15, from the sorghum pathogen Cochliobolus lunatus, is involved in
detoxification of benzoate, a key intermediate in aromatic compound metabolism in fungi …

Cinnamic acid derivatives are known antifungal, antimicrobial, antioxidant, and anticancer
compounds. We have developed a facile and mild methodology for the synthesis of (E) …

The mosquito Aedes aegypti transmits the virus that causes dengue, yellow fever, Zika and
Chikungunya viruses, and in several regions of the planet represents a vector of great …

Leishmania braziliensis is one of the pathogenic agents of cutaneous and mucocutanoeous
leishmaniasis. There are no validated vaccines to prevent the infection and the treatment …