Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds

HM Scott, JI Mason, RM Sharpe - Endocrine reviews, 2009 - academic.oup.com
Masculinization depends on adequate production of testosterone by the fetal testis within a
specific “masculinization programming window.” Disorders resulting from subtle deficiencies …

Safety issues and prospects for future generations of PPAR modulators

A Rubenstrunk, R Hanf, DW Hum, JC Fruchart… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Because of their wide range of actions on glucose homeostasis, lipid metabolism and
vascular inflammation, peroxisome proliferator-activated receptors (PPARs) are promising …

[图书][B] Drugs in pregnancy and lactation: a reference guide to fetal and neonatal risk

GG Briggs, RK Freeman, SJ Yaffe - 2011 - books.google.com
An AZ listing of drugs by generic name. Each monograph summarizes the known and/or
possible effects of the drug on the fetus. It also summarizes the known/possible passage of …

The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)

MA Peraza, AD Burdick, HE Marin… - Toxicological …, 2006 - academic.oup.com
Peroxisome proliferator-activated receptors (PPARs) are ligand activated transcription
factors that modulate target gene expression in response to endogenous and exogenous …

Effectiveness and safety of available treatments for COVID-19 during pregnancy: a critical review

A Favilli, M Mattei Gentili, F Raspa… - The Journal of …, 2022 - Taylor & Francis
Background COVID-19 is a pandemic disease caused by the SARS-CoV-2 and it spread
globally in the last few months. The complete lack of specific treatment forced clinicians to …

Probiotic treatment reduces blood glucose levels and increases systemic absorption of gliclazide in diabetic rats

H Al-Salami, G Butt, JP Fawcett, IG Tucker… - European journal of …, 2008 - Springer
The action of gliclazide, a sulphonylurea with beneficial extrapancreatic effects in diabetes,
may be enhanced by administering probiotics. The aim of this study was to investigate the …

Pravastatin for preventing and treating preeclampsia: a systematic review

E Esteve-Valverde, R Ferrer-Oliveras… - Obstetrical & …, 2018 - journals.lww.com
Pravastatin for Preventing and Treating Preeclampsia: A Syst... : Obstetrical & Gynecological
Survey Pravastatin for Preventing and Treating Preeclampsia: A Systematic Review …

[HTML][HTML] Fetal toxicity associated with statins: A systematic review and meta-analysis

A Vahedian-Azimi, S Makvandi, M Banach, Ž Reiner… - Atherosclerosis, 2021 - Elsevier
Background and aims Statins are the drugs of choice for decreasing elevated low-density
lipoprotein cholesterol. Based mostly on animal studies and case reports, they are forbidden …

Statin use during pregnancy: a systematic review and meta-analysis

DM Kusters, HH Lahsinoui… - Expert review of …, 2012 - Taylor & Francis
Statins enjoy widespread acceptance as effective drugs to reduce morbidity and mortality in
patients with and without cardiovascular disease, and are considered safe for long-term use …

The pleiotropic function of PPARγ in the placenta

WT Schaiff, Y Barak, Y Sadovsky - Molecular and Cellular Endocrinology, 2006 - Elsevier
At different stages of placental development the cytotrophoblasts differentiate into
specialized cells that are vital for specific placental tasks. These types include the invasive …