Characterization of conductivity changes during high-frequency irreversible electroporation for treatment planning

Y Zhao, S Bhonsle, S Dong, Y Lv, H Liu… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
For irreversible-electroporation (IRE)-based therapies, the underlying electric field
distribution in the target tissue is influenced by the electroporation-induced conductivity …

The Influence of Irreversible Electroporation Parameters on the Size of the Ablation Zone and Thermal Effects: A Systematic Review

AM Hogenes, CG Overduin, CH Slump… - … in Cancer Research …, 2023 - journals.sagepub.com
Introduction: The aim of this study was to review the effect of irreversible electroporation
parameter settings on the size of the ablation zone and the occurrence of thermal effects …

Effects of internal electrode cooling on irreversible electroporation using a perfused organ model

TJ O'Brien, M Bonakdar, S Bhonsle… - International Journal …, 2018 - Taylor & Francis
Purpose: This study evaluates the effects of active electrode cooling, via internal fluid
circulation, on the irreversible electroporation (IRE) lesion, deployed electric current and …

Experimental high-frequency irreversible electroporation using a single-needle delivery approach for nonthermal pancreatic ablation in vivo

TJ O'Brien, M Passeri, MF Lorenzo, JK Sulzer… - Journal of Vascular and …, 2019 - Elsevier
Purpose To investigate the feasibility of single-needle high-frequency irreversible
electroporation (SN-HFIRE) to create reproducible tissue ablations in an in vivo pancreatic …

[HTML][HTML] Intraoperative electrochemotherapy of colorectal liver metastases: A prospective phase II study

I Edhemovic, E Brecelj, M Cemazar, N Boc… - European Journal of …, 2020 - Elsevier
Background and objectives A previous pilot study proved the feasibility, safety and efficacy
of electrochemotherapy in the treatment of colorectal liver metastases. The aim of this study …

Predicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomography

M Kranjc, S Kranjc, F Bajd, G Serša, I Serša… - Scientific reports, 2017 - nature.com
Irreversible electroporation (IRE) is gaining importance in routine clinical practice for
nonthermal ablation of solid tumors. For its success, it is extremely important that the …

Device and methods for delivery of high frequency electrical pulses for non-thermal ablation

B Christopher, RV Davalos, MB Sano - US Patent 11,382,681, 2022 - Google Patents
The present invention relates to the field of biomedical engineering and medical treatment of
diseases and disorders. Methods, devices, and systems for in vivo treatment of cell …

Electrical characterization of human biological tissue for irreversible electroporation treatments

N Beitel-White, S Bhonsle, RCG Martin… - 2018 40th Annual …, 2018 - ieeexplore.ieee.org
Irreversible electroporation (IRE) is a cancer therapy that uses short, high-voltage electrical
pulses to treat tumors. Due to its predominantly non-thermal mechanism and ability to ablate …

Methods for delivery of biphasic electrical pulses for non-thermal ablation

RV Davalos, PA Garcia, JH Rossmeisl… - US Patent …, 2022 - Google Patents
The present invention provides systems, methods, and devices for electroporation-based
therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the …

Devices and methods for high frequency electroporation

IIRE Neal, PA Garcia, RV Davalos… - US Patent …, 2022 - Google Patents
2019-06-10 Assigned to VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
reassignment VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ASSIGNMENT OF …