Ras homolog gene family member A (RhoA) is a small GTPase of the Rho family involved in
regulating multiple signal transduction pathways that influence a diverse range of cellular …

The Rho subfamily members of Rho GTPases, RhoA, RhoB, and RhoC, are key regulators
of signal transduction in a variety of cellular processes, including regulation of actomyosin …

With an increasing proportion of drug-resistant bacteria, photothermal therapy (PTT) is a
promising alternative to antibiotic treatment for infected diabetic skin ulcers. However, the …

In the tumor microenvironment (TME), communication between cancer cells and tumor-
associated macrophages (TAMs) through secreted extracellular proteins promotes cancer …

Src, a non-receptor tyrosine kinase, was first discovered as a prototype oncogene and has
been shown to critical for cancer progression for a variety of tissues. Src activity is regulated …

Insulin potently promotes cell proliferation and anabolic metabolism along with a reduction
in blood glucose levels. Pyruvate dehydrogenase (PDH) plays a pivotal role in glucose …

Inflammation plays a crucial role in tumorigenesis, primarily mediated by NF-κB. RhoA
GTPases are instrumental in regulating the activation of NF-κB. Specifically, the …

Epidermal growth factor (EGF) is known to be a critical stimulant for inducing the proliferation
of glioma cancer cells. In our study, we observed that GST‐RhoA binds to pyruvate kinase …

Osteosarcoma is the most prevalent form of primary bone malignancy affecting adolescents.
Secretion‐associated Ras‐related GTPase 1A (SAR1A) is a key regulator of endoplasmic …

Rho GTPases are critically important and are centrally positioned regulators of the
actomyosin cytoskeleton. By influencing the organization and architecture of the …