Unveiling the connection: long-chain non-coding RNAs and critical signaling pathways in breast cancer
Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …
essential for cell proliferation, survival, and differentiation. Recently, the significant …
Epigenetic modifications in cancer
Kanwal R, Gupta S. Epigenetic modifications in cancer. Cancer initiation and progression is
controlled by both genetic and epigenetic events. The complexity of carcinogenesis cannot …
controlled by both genetic and epigenetic events. The complexity of carcinogenesis cannot …
[HTML][HTML] IGF2 and cancer
C Livingstone - Endocrine-related cancer, 2013 - erc.bioscientifica.com
Insulin-like growth factor 2 (IGF2) is a 7.5 kDa mitogenic peptide hormone expressed by liver
and many other tissues. It is three times more abundant in serum than IGF1, but our …
and many other tissues. It is three times more abundant in serum than IGF1, but our …
The type 1 insulin-like growth factor receptor pathway
Research conducted over the past two decades has shown the importance of the type 1
insulin-like growth factor receptor (IGF1R) in tumorigenesis, metastasis, and resistance to …
insulin-like growth factor receptor (IGF1R) in tumorigenesis, metastasis, and resistance to …
[HTML][HTML] Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility
OBJECTIVE: To evaluate the associations between proper protamine incorporation and
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …
The role of DNA methylation in cancer
R Lakshminarasimhan, G Liang - DNA Methyltransferases-Role and …, 2016 - Springer
The malignant transformation of normal cells is driven by both genetic and epigenetic
changes. With the advent of next-generation sequencing and large-scale multinational …
changes. With the advent of next-generation sequencing and large-scale multinational …
Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke
SK Murphy, A Adigun, Z Huang, F Overcash, F Wang… - Gene, 2012 - Elsevier
Epigenetic alterations may mechanistically explain the developmental origins of adult
disease, namely the hypothesis that many complex adult chronic diseases originate as a …
disease, namely the hypothesis that many complex adult chronic diseases originate as a …
DNA hypomethylation in the origin and pathogenesis of human diseases
IP Pogribny, FA Beland - Cellular and Molecular Life Sciences, 2009 - Springer
The pathogenesis of any given human disease is a complex multifactorial process
characterized by many biologically significant and interdependent alterations. One of these …
characterized by many biologically significant and interdependent alterations. One of these …
DNA methylation in social insects: how epigenetics can control behavior and longevity
In eusocial insects, genetically identical individuals can exhibit striking differences in
behavior and longevity. The molecular basis of such phenotypic plasticity is of great interest …
behavior and longevity. The molecular basis of such phenotypic plasticity is of great interest …
Regulation of H19 and its encoded microRNA-675 in osteoarthritis and under anabolic and catabolic in vitro conditions
E Steck, S Boeuf, J Gabler, N Werth… - Journal of molecular …, 2012 - Springer
Cartilage degeneration in the course of osteoarthritis (OA) is associated with an alteration in
chondrocyte metabolism. In order to identify molecules representing putative key regulators …
chondrocyte metabolism. In order to identify molecules representing putative key regulators …