[HTML][HTML] Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease

L De Franceschi, RS Franco, M Bertoldi… - The FASEB …, 2013 - ncbi.nlm.nih.gov
Sickle cell disease (SCD) is a globally distributed hereditary red blood cell (RBC) disorder.
One of the hallmarks of SCD is the presence of circulating dense RBCs, which are important …

[PDF][PDF] Calcium handling in red blood cells of sickle cell disease patients

A Bogdanova, A Makhro, L Kaestner - Sickle Cell Disease, ed ME …, 2015 - researchgate.net
Precise control over the intracellular free Ca2+ level is of key importance for any cell, red
blood cells (RBCs) included. Cell fate of erythroid precursor cells, as well as volume, redox …

Association between plasma membrane (Ca+ Mg) ATPase and calpain/calpastatin system in rat erythrocytes

L Soldati, G Vezzoli, S Salardi, R Spaventa… - Biochemical and …, 1996 - Elsevier
We studied the activity of plasma membrane (Ca+ Mg) ATPase from erythrocytes of Milan
hypertensive rat strain (MHS) and Milan low calpastatin rat strain (MLCS), that show an …