The central nervous system (CNS) and its meningeal coverings accommodate a diverse
myeloid compartment that includes parenchymal microglia and perivascular macrophages …

Interferons (IFNs) are implicated as an important component of the innate immune system
influencing viral infections, inflammation, and immune surveillance. We review here the …

Central nervous system B cells have several potential roles in multiple sclerosis (MS):
secretors of proinflammatory cytokines and chemokines, presenters of autoantigens to T …

Objective To identify and characterize myeloid cell populations within the CSF of patients
with MS and anti-myelin oligodendrocyte glycoprotein (MOG) disorder by high-resolution …

We performed unbiased, comprehensive immunophenotyping of cerebrospinal fluid (CSF)
and blood leukocytes in 221 subjects referred for the diagnostic work-up of …

This paper proposes a neuro-immune model for Myalgic Encephalomyelitis/Chronic fatigue
syndrome (ME/CFS). A wide range of immunological and neurological abnormalities have …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
related to autoimmunity and is characterized by demyelination, neuroinflammation, and …

Autoimmune diseases affect about one in 15 individuals in developed countries and are
characterized by a breakdown in immune tolerance. Current therapeutic approaches against …

Many studies have demonstrated the role of the adaptive immune system in the
pathogenesis of multiple sclerosis (MS). Recent data suggest that dendritic cells (DCs) …

Plasmacytoid dendritic cells (pDCs) have been shown to both mediate and prevent
autoimmunity, and the regulation of their immunogenic versus tolerogenic functions remains …