The integrated brain network that controls respiration
F Krohn, M Novello, RS van der Giessen, CI De Zeeuw… - Elife, 2023 - elifesciences.org
Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …
Diversity and dynamism in the cerebellum
CI De Zeeuw, SG Lisberger, JL Raymond - Nature neuroscience, 2021 - nature.com
The past several years have brought revelations and paradigm shifts in research on the
cerebellum. Historically viewed as a simple sensorimotor controller with homogeneous …
cerebellum. Historically viewed as a simple sensorimotor controller with homogeneous …
Polyglutamine spinocerebellar ataxias—from genes to potential treatments
HL Paulson, VG Shakkottai, HB Clark… - Nature Reviews …, 2017 - nature.com
The dominantly inherited spinocerebellar ataxias (SCAs) are a large and diverse group of
neurodegenerative diseases. The most prevalent SCAs (SCA1, SCA2, SCA3, SCA6 and …
neurodegenerative diseases. The most prevalent SCAs (SCA1, SCA2, SCA3, SCA6 and …
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
PT Tsai, C Hull, YX Chu, E Greene-Colozzi… - Nature, 2012 - nature.com
Autism spectrum disorders (ASDs) are highly prevalent neurodevelopmental disorders, but
the underlying pathogenesis remains poorly understood. Recent studies have implicated the …
the underlying pathogenesis remains poorly understood. Recent studies have implicated the …
Bidirectional learning in upbound and downbound microzones of the cerebellum
CI De Zeeuw - Nature Reviews Neuroscience, 2021 - nature.com
Over the past several decades, theories about cerebellar learning have evolved. A relatively
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …
Encoding of action by the Purkinje cells of the cerebellum
Execution of accurate eye movements depends critically on the cerebellum,,, suggesting that
the major output neurons of the cerebellum, Purkinje cells, may predict motion of the eye …
the major output neurons of the cerebellum, Purkinje cells, may predict motion of the eye …
Distributed synergistic plasticity and cerebellar learning
Z Gao, BJ Van Beugen, CI De Zeeuw - Nature Reviews Neuroscience, 2012 - nature.com
Studies on synaptic plasticity in the context of learning have been dominated by the view
that a single, particular type of plasticity forms the underlying mechanism for a particular type …
that a single, particular type of plasticity forms the underlying mechanism for a particular type …
Seeking a unified framework for cerebellar function and dysfunction: from circuit operations to cognition
E D'Angelo, S Casali - Frontiers in neural circuits, 2013 - frontiersin.org
Following the fundamental recognition of its involvement in sensory-motor coordination and
learning, the cerebellum is now also believed to take part in the processing of cognition and …
learning, the cerebellum is now also believed to take part in the processing of cognition and …
The cerebellar cortex
The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …
Cerebellar modules operate at different frequencies
Due to the uniform cyto-architecture of the cerebellar cortex, its overall physiological
characteristics have traditionally been considered to be homogeneous. In this study, we …
characteristics have traditionally been considered to be homogeneous. In this study, we …