Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

This review highlights recent efforts on applying electron microscopy (EM) to soft (including
biological) nanomaterials. We will show how developments of both the hardware and …

As a progressive, irreversible neurodegenerative disease, Alzheimer's disease (AD)
continues to be a serious public health problem worldwide. Currently, the most available …

Multifunctional magnetic nanoparticles (NPs) that can generate and monitor heat (in real-
time) during thermal therapy are a major challenge in nanomedicine. Here, we report a …

Liquid–liquid phase separation (LLPS) and liquid crystalline (LC) ordering are ubiquitous
phenomena in nature, in a variety of biomolecular solutions. Here, we review instances in …

Nanoscale morphology of functional materials determines their chemical and physical
properties. However, despite increasing use of transmission electron microscopy (TEM) to …

Amyloid diseases are global epidemics with no cure currently available. In the past decade,
the use of engineered nanomaterials as inhibitors or probes against the pathogenic …

Amyloid protein cross-seeding is a peculiar phenomenon of cross-spreading among
different diseases. Unlike traditional infectious ones, diseases caused by amyloid protein …

The ongoing development of liquid-phase electron microscopy methods—in which
specimens are kept fully solvated in the microscope by encapsulation in transparent …

The vast majority of nanomedicines (NM) investigated today consists of a macromolecular
carrier and a drug payload (conjugated or encapsulated), with a purpose of preferential …