Ischemic stroke (IS) is one of the leading causes of death and disability resulting in
inevitable burden globally. Ischemic injury initiates cascade of pathological events …

NEET proteins belong to a highly conserved group of [2Fe–2S] proteins found across all
kingdoms of life. Due to their unique [2Fesingle bond2S] cluster structure, they play a key …

Hyperglycemia is a risk factor for poor prognosis after acute ischemic stroke and promote the
occurrence of hemorrhagic transformation (HT). The activation of P2RX7 play an important …

Brain is by far the most complex organ in the body. It is involved in the regulation of
cognitive, behavioral, and emotional activities. The organ is also a target for many diseases …

Ischemia reperfusion (IR)-induced oxidative stress, accompanied by inflammatory
responses, contributes to morbidity and mortality in numerous diseases such as acute …

With the accelerated development of nanotechnology in recent years, nanomaterials have
become increasingly prevalent in the medical field. The poly (lactic acid–glycolic acid) …

NL-1 is a mitoNEET ligand known for its antileukemic effects and has recently shown
neuroprotective effects in an ischemic stroke model. However, its underlying process in …

Stroke accounts for one of the top leading reasons for neurological mortality and morbidity
around the globe. Both ischemic and hemorrhagic strokes lead to local hypoxia and are …

Purpose Therapeutic strategies to treat ischemic stroke are limited due to the heterogeneity
of cerebral ischemic injury and the mechanisms that contribute to the cell death. Since …

Cerebral ischemic stroke is a leading cause of mortality and disability worldwide. Currently,
there are a lack of drugs capable of reducing neuronal cell loss due to ischemia/reperfusion …