MicroRNAs (miRNAs) bind to complementary target RNAs and regulate their gene
expression post-transcriptionally. These non-coding regulatory RNAs become functional …

Small-RNA-guided gene regulation has emerged as one of the fundamental principles in
cell function, and the major protein players in this process are members of the Argonaute …

Post‐transcriptional regulation of messenger RNAs (mRNAs)(ie, mechanisms that control
translation, stability and localization) is a critical focal point in spatiotemporal regulation of …

Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers
worldwide and the fourth most lethal cancer in China. However, although genomic studies …

Tissue mechanics regulate development and homeostasis and are consistently modified in
tumor progression. Nevertheless, the fundamental molecular mechanisms through which …

Abstract Pachytene PIWI-interacting RNAs (piRNAs), which comprise> 80% of small RNAs
in the adult mouse testis, have been proposed to bind and regulate target RNAs like …

Considerable evidence suggests that autism spectrum disorders (ASD), schizophrenia
(SCZ), bipolar disorder (BD) and obsessive-compulsive disorder (OCD) share a common …

Many neurodegenerative diseases are characterized by the presence of intracellular protein
aggregates, resulting in alterations in autophagy. However, the consequences of impaired …

Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton
and transduce signals in response to both chemical and mechanical cues. The composition …

Cells sense and respond to extracellular mechanical cues through cell-matrix adhesions.
Interestingly, the maturation of focal adhesions (FAs) is reciprocally force dependent. How …