Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis
Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss. Significant
variations in the clinical presentation of AA have been observed, ranging from small, well …
variations in the clinical presentation of AA have been observed, ranging from small, well …
Alopecia areata: a review of disease pathogenesis
Background Alopecia areata is a disorder that results in nonscarring hair loss. The
psychological impact can be significant, leading to feelings of depression and social …
psychological impact can be significant, leading to feelings of depression and social …
The melanocyte lineage in development and disease
RL Mort, IJ Jackson, EE Patton - Development, 2015 - journals.biologists.com
Melanocyte development provides an excellent model for studying more complex
developmental processes. Melanocytes have an apparently simple aetiology, differentiating …
developmental processes. Melanocytes have an apparently simple aetiology, differentiating …
Molecular genetic variation of animals and plants under domestication
L Andersson, M Purugganan - Proceedings of the National …, 2022 - National Acad Sciences
Domesticated plants and animals played crucial roles as models for evolutionary change by
means of natural selection and for establishing the rules of inheritance, originally proposed …
means of natural selection and for establishing the rules of inheritance, originally proposed …
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
L Petukhova, M Duvic, M Hordinsky, D Norris, V Price… - Nature, 2010 - nature.com
Alopecia areata (AA) is among the most highly prevalent human autoimmune diseases,
leading to disfiguring hair loss due to the collapse of immune privilege of the hair follicle and …
leading to disfiguring hair loss due to the collapse of immune privilege of the hair follicle and …
[HTML][HTML] An integrated approach to uncover drivers of cancer
Systematic characterization of cancer genomes has revealed a staggering number of
diverse aberrations that differ among individuals, such that the functional importance and …
diverse aberrations that differ among individuals, such that the functional importance and …
Canine melanomas as models for human melanomas: clinical, histological, and genetic comparison
A Prouteau, C André - Genes, 2019 - mdpi.com
Despite recent genetic advances and numerous ongoing therapeutic trials, malignant
melanoma remains fatal, and prognostic factors as well as more efficient treatments are …
melanoma remains fatal, and prognostic factors as well as more efficient treatments are …
Genome-wide analysis reveals selection for important traits in domestic horse breeds
Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …
Colours of domestication
M Cieslak, M Reissmann, M Hofreiter… - Biological …, 2011 - Wiley Online Library
During the last decade, coat colouration in mammals has been investigated in numerous
studies. Most of these studies addressing the genetics of coat colouration were on …
studies. Most of these studies addressing the genetics of coat colouration were on …
An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts
MP Hoeppner, A Lundquist, M Pirun, JRS Meadows… - PloS one, 2014 - journals.plos.org
The domestic dog, Canis familiaris, is a well-established model system for mapping trait and
disease loci. While the original draft sequence was of good quality, gaps were abundant …
disease loci. While the original draft sequence was of good quality, gaps were abundant …