Alopecia areata: disease characteristics, clinical evaluation, and new perspectives on pathogenesis

LC Strazzulla, EHC Wang, L Avila, KL Sicco… - Journal of the American …, 2018 - Elsevier
Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss. Significant
variations in the clinical presentation of AA have been observed, ranging from small, well …

Alopecia areata: a review of disease pathogenesis

F Rajabi, LA Drake, MM Senna… - British Journal of …, 2018 - academic.oup.com
Background Alopecia areata is a disorder that results in nonscarring hair loss. The
psychological impact can be significant, leading to feelings of depression and social …

The melanocyte lineage in development and disease

RL Mort, IJ Jackson, EE Patton - Development, 2015 - journals.biologists.com
Melanocyte development provides an excellent model for studying more complex
developmental processes. Melanocytes have an apparently simple aetiology, differentiating …

Molecular genetic variation of animals and plants under domestication

L Andersson, M Purugganan - Proceedings of the National …, 2022 - National Acad Sciences
Domesticated plants and animals played crucial roles as models for evolutionary change by
means of natural selection and for establishing the rules of inheritance, originally proposed …

Genome-wide association study in alopecia areata implicates both innate and adaptive immunity

L Petukhova, M Duvic, M Hordinsky, D Norris, V Price… - Nature, 2010 - nature.com
Alopecia areata (AA) is among the most highly prevalent human autoimmune diseases,
leading to disfiguring hair loss due to the collapse of immune privilege of the hair follicle and …

[HTML][HTML] An integrated approach to uncover drivers of cancer

UD Akavia, O Litvin, J Kim, F Sanchez-Garcia, D Kotliar… - Cell, 2010 - cell.com
Systematic characterization of cancer genomes has revealed a staggering number of
diverse aberrations that differ among individuals, such that the functional importance and …

Canine melanomas as models for human melanomas: clinical, histological, and genetic comparison

A Prouteau, C André - Genes, 2019 - mdpi.com
Despite recent genetic advances and numerous ongoing therapeutic trials, malignant
melanoma remains fatal, and prognostic factors as well as more efficient treatments are …

Genome-wide analysis reveals selection for important traits in domestic horse breeds

JL Petersen, JR Mickelson, AK Rendahl… - PLoS …, 2013 - journals.plos.org
Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …

Colours of domestication

M Cieslak, M Reissmann, M Hofreiter… - Biological …, 2011 - Wiley Online Library
During the last decade, coat colouration in mammals has been investigated in numerous
studies. Most of these studies addressing the genetics of coat colouration were on …

An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts

MP Hoeppner, A Lundquist, M Pirun, JRS Meadows… - PloS one, 2014 - journals.plos.org
The domestic dog, Canis familiaris, is a well-established model system for mapping trait and
disease loci. While the original draft sequence was of good quality, gaps were abundant …