Human immunoglobulin preparations for intravenous or subcutaneous administration are
the cornerstone of treatment in patients with primary immunodeficiency diseases affecting …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

The International Collaboration in Asthma, Allergy and Immunology initiated an international
coalition among the American Academy of Allergy, Asthma & Immunology; the European …

Background Activated phosphoinositide 3-kinase δ syndrome (APDS) is a recently
described combined immunodeficiency resulting from gain-of-function mutations in PIK3CD …

The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

Background Common variable immunodeficiency (CVID) is an antibody deficiency with an
equal sex distribution and a high variability in clinical presentation. The main features …

Non-infectious complications in common variable immunodeficiency (CVID) have emerged
as a major clinical challenge. Detailed clinical spectrum, organ-specific pathologies and …

Placental transfer of maternal IgG antibodies to the fetus is an important mechanism that
provides protection to the infant while his/her humoral response is inefficient. IgG is the only …

Health disparities are health differences linked with economic, social, and environmental
disadvantage. They adversely affect groups that have systematically experienced greater …

The demographics, immunologic parameters, medical complications, and mortality statistics
from 473 subjects with common variable immune deficiency followed over 4 decades in New …