Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

[HTML][HTML] Unique diagnostic and therapeutic roles of porphyrins and phthalocyanines in photodynamic therapy, imaging and theranostics

LB Josefsen, RW Boyle - Theranostics, 2012 - ncbi.nlm.nih.gov
Porphyrinic molecules have a unique theranostic role in disease therapy; they have been
used to image, detect and treat different forms of diseased tissue including age-related …

Oncologic photodynamic therapy photosensitizers: a clinical review

RR Allison, CH Sibata - Photodiagnosis and photodynamic therapy, 2010 - Elsevier
A myriad of naturally occurring and synthetic structures are capable of transferring the
energy of light. Few, however, allow for this energy transfer to enable a type II photochemical …

Basic principles of photodynamic therapy

IJ Macdonald, TJ Dougherty - Journal of porphyrins and …, 2001 - World Scientific
The therapeutic use of light, as we know it, begins in 1900 when Raab reported that the
combination of acridine orange and light could destroy living organisms (paramecium)[1]. In …

Photosensitizers in clinical PDT

RR Allison, GH Downie, R Cuenca, XH Hu… - Photodiagnosis and …, 2004 - Elsevier
Photosensitizers in photodynamic therapy allow for the transfer and translation of light
energy into a type II chemical reaction. In clinical practice, photosensitizers arise from three …

In vivo fluorescence spectroscopy and imaging for oncological applications

GA Wagnieres, WM Star… - Photochemistry and …, 1998 - search.proquest.com
Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

Like a bolt from the blue: phthalocyanines in biomedical optics

N Sekkat, H van den Bergh, T Nyokong, N Lange - Molecules, 2011 - mdpi.com
The purpose of this review is to compile preclinical and clinical results on phthalocyanines
(Pcs) as photosensitizers (PS) for Photodynamic Therapy (PDT) and contrast agents for …

Improved detection of urothelial carcinoma in situ with hexaminolevulinate fluorescence cystoscopy

J Schmidbauer, F Witjes, N Schmeller… - The Journal of …, 2004 - auajournals.org
ABSTRACT Purpose: In this European multicenter study we compared hexaminolevulinate
(HAL) fluorescence cystoscopy and standard white light cystoscopy for the detection of …

A comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of carcinoma in situ in patients with bladder cancer: a phase …

Y Fradet, HB Grossman, L Gomella, S Lerner… - The Journal of …, 2007 - auajournals.org
Purpose: We compared hexaminolevulinate (Hexvix®) fluorescence cystoscopy with white
light cystoscopy for detecting carcinoma in situ. Materials and Methods: In this multicenter …

Improved detection and treatment of bladder cancer using hexaminolevulinate imaging: a prospective, phase III multicenter study

D Jocham, F Witjes, S Wagner, B Zeylemaker… - The Journal of …, 2005 - auajournals.org
Purpose: We determined if improved tumor detection using hexaminolevulinate (HAL)
fluorescence cystoscopy could lead to improved treatment in patients with bladder cancer …