Major depressive disorder (MDD) is one of the most prevalent and debilitating disorders.
Current available treatments are somehow limited, so alternative therapeutic approaches …

The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …

Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

Oxidative stress is a well-known risk factor for the development of anxiety and depression
disorders. Curcumin, a natural compound, is an antioxidant with well-known neuroprotective …

Curcumin is the major biologically active polyphenolic constituent in the turmeric plant
(Curcuma longa) that has been shown to have antioxidant, anti-inflammatory …

Background: The current study utilizes in silico molecular docking/molecular dynamics to
evaluate the binding affinity of apigenin and safranal with 5HT1AR/5HT2AR, followed by …

Numerous animal and human studies have assessed the relationship between polyphenols
and outcomes related to depression. However, no comprehensive synthesis of the main …

Mesenchymal stem cells derived from bone marrows (BMSCs) and curcumin derived from
turmeric were used for osteoarthritis (OA) treatment, respectively. We invested the effects of …

Clinical evidence indicates that major depression is a common comorbidity of chronic pain,
including neuropathic pain; however, the cellular basis for chronic pain-mediated major …

It has been consistently found that exposure to ambient air pollution, such as particulate
matter (PM), results in cognitive impairments and mental disorders. This study aimed to …