Neuroprotective effects of thiamine and precursors with higher bioavailability: focus on benfotiamine and dibenzoylthiamine
M Sambon, P Wins, L Bettendorff - International journal of molecular …, 2021 - mdpi.com
Thiamine (vitamin B1) is essential for brain function because of the coenzyme role of
thiamine diphosphate (ThDP) in glucose and energy metabolism. In order to compensate …
thiamine diphosphate (ThDP) in glucose and energy metabolism. In order to compensate …
Antioxidants in potatoes: A functional view on one of the major food crops worldwide
With a growing world population, accelerating climate changes, and limited arable land, it is
critical to focus on plant-based resources for sustainable food production. In addition, plants …
critical to focus on plant-based resources for sustainable food production. In addition, plants …
Benfotiamine and cognitive decline in Alzheimer's disease: results of a randomized placebo-controlled phase IIa clinical trial
GE Gibson, JA Luchsinger, R Cirio… - Journal of …, 2020 - content.iospress.com
Background: In preclinical models, benfotiamine efficiently ameliorates the clinical and
biological pathologies that define Alzheimer's disease (AD) including impaired cognition …
biological pathologies that define Alzheimer's disease (AD) including impaired cognition …
Synthetic Thioesters of Thiamine: Promising Tools for Slowing Progression of Neurodegenerative Diseases
L Bettendorff - International Journal of Molecular Sciences, 2023 - mdpi.com
Thiamine (vitamin B1) is essential for the brain. This is attributed to the coenzyme role of
thiamine diphosphate (ThDP) in glucose and energy metabolism. The synthetic thiamine …
thiamine diphosphate (ThDP) in glucose and energy metabolism. The synthetic thiamine …
Thiamine demonstrates bio-preservative and anti-microbial effects in minced beef meat storage and lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages
Simple Summary Thiamine (TA), also known as vitamin B1, is an essential amino acid
derived from food sources for normal body function. TA is thought to have antioxidant …
derived from food sources for normal body function. TA is thought to have antioxidant …
Neuroblastoma is associated with alterations in gut microbiome composition subsequent to maternal microbial seeding
Background Neuroblastoma is the most frequent extracranial solid tumour in children,
accounting for∼ 15% of deaths due to cancer in childhood. The most common clinical …
accounting for∼ 15% of deaths due to cancer in childhood. The most common clinical …
Thiamine and benfotiamine: Focus on their therapeutic potential
I Bozic, I Lavrnja - Heliyon, 2023 - cell.com
Thiamine, also known as vitamin B1, is an essential nutrient that plays a crucial role in
energy metabolism and overall health. It is a water-soluble vitamin that plays an important …
energy metabolism and overall health. It is a water-soluble vitamin that plays an important …
Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration
Thiamine precursors, the most studied being benfotiamine (BFT), have protective effects in
mouse models of neurodegenerative diseases. BFT decreased oxidative stress and …
mouse models of neurodegenerative diseases. BFT decreased oxidative stress and …
Emerging Alzheimer's disease therapeutics: promising insights from lipid metabolism and microglia-focused interventions
NS Tobeh, KD Bruce - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
More than 55 million people suffer from dementia, with this number projected to double
every 20 years. In the United States, 1 in 3 aged individuals dies from Alzheimer's disease …
every 20 years. In the United States, 1 in 3 aged individuals dies from Alzheimer's disease …
Role of the synthetic B1 vitamin sulbutiamine on health
B Starling-Soares, P Carrera-Bastos… - Journal of nutrition …, 2020 - Wiley Online Library
Sulbutiamine is a thiamine derivative developed in Japan in the mid‐60's as a beriberi
treatment drug. Since then, different potential applications have been described. For …
treatment drug. Since then, different potential applications have been described. For …