Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

The role of NPY in hypothalamic mediated food intake

RE Mercer, MJS Chee, WF Colmers - Frontiers in neuroendocrinology, 2011 - Elsevier
Neuropeptide Y (NPY) is a highly conserved neuropeptide with orexigenic actions in
discrete hypothalamic nuclei that plays a role in regulating energy homeostasis. NPY …

Neuropeptides and central control of sexual behaviour from the past to the present: a review

A Argiolas, MR Melis - Progress in neurobiology, 2013 - Elsevier
Of the numerous neuropeptides identified in the central nervous system, only a few are
involved in the control of sexual behaviour. Among these, the most studied are oxytocin …

Galanin receptors and ligands

KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …

Circadian Regulation of Kiss1 Neurons: Implications for Timing the Preovulatory Gonadotropin-Releasing Hormone/Luteinizing Hormone Surge

JL Robertson, DK Clifton, HO de la Iglesia… - …, 2009 - academic.oup.com
The preovulatory GnRH/LH surge depends on the presence of estradiol (E2) and is gated by
a circadian oscillator in the suprachiasmatic nucleus (SCN) that causes the surge to occur …

The kisspeptin receptor GPR54 is required for sexual differentiation of the brain and behavior

AS Kauffman, JH Park… - Journal of …, 2007 - Soc Neuroscience
GPR54 is a G-protein-coupled receptor, which binds kisspeptins and is widely expressed
throughout the brain. Kisspeptin–GPR54 signaling has been implicated in the regulation of …

Neuropeptide signaling in the integration of metabolism and reproduction

A Crown, DK Clifton, RA Steiner - Neuroendocrinology, 2007 - karger.com
Fertility is gated by nutrition and the availability of stored energy reserves, but the cellular
and molecular mechanisms that link energy stores and reproduction are not well …

Neuropeptides and behaviors: how small peptides regulate nervous system function and behavioral outputs

US Bhat, N Shahi, S Surendran, K Babu - Frontiers in Molecular …, 2021 - frontiersin.org
One of the reasons that most multicellular animals survive and thrive is because of the
adaptable and plastic nature of their nervous systems. For an organism to survive, it is …