Microbiome and human aging: probiotic and prebiotic potentials in longevity, skin health and cellular senescence
The role of the microbiome in human aging is important: the microbiome directly impacts
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …
aging through the gastrointestinal system. However, the microbial impact on skin has yet to …
Are we ill because we age?
Growing elderly populations, sometimes referred to as gray (or silver) tsunami, are an
increasingly serious health and socioeconomic concern for modern societies. Science has …
increasingly serious health and socioeconomic concern for modern societies. Science has …
Anti-aging activity and modes of action of compounds from natural food sources
L Song, S Zhang - Biomolecules, 2023 - mdpi.com
Aging is a natural and inescapable phenomenon characterized by a progressive
deterioration of physiological functions, leading to increased vulnerability to chronic …
deterioration of physiological functions, leading to increased vulnerability to chronic …
Experimental evidence for cancer resistance in a bat species
R Hua, YS Ma, L Yang, JJ Hao, QY Hua, LY Shi… - Nature …, 2024 - nature.com
Mammals exhibit different rates of cancer, with long-lived species generally showing greater
resistance. Although bats have been suggested to be resistant to cancer due to their …
resistance. Although bats have been suggested to be resistant to cancer due to their …
Bcl-xL as a Modulator of Senescence and Aging
C Mas-Bargues, C Borrás, J Viña - International journal of molecular …, 2021 - mdpi.com
Many features of aging result from the incapacity of cells to adapt to stress conditions. When
cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth …
cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth …
Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation
Naked mole-rats (NMRs) have amongst the longest lifespans relative to body size of any
known, non-volant mammalian species. They also display an enhanced stress resistance …
known, non-volant mammalian species. They also display an enhanced stress resistance …
In Vitro Investigation of the Anticancer Properties of Ammodaucus Leucotrichus Coss. & Dur.
M Lenzi, E Turrini, E Catanzaro, V Cocchi, A Guerrini… - Pharmaceuticals, 2022 - mdpi.com
Little is known about the pharmacological activity of Ammodaucus leucotrichus Coss. & Dur.,
a small annual species that grows in the Saharan and sub-Saharan countries. In the present …
a small annual species that grows in the Saharan and sub-Saharan countries. In the present …
Contribution of cerebral microvascular mechanisms to age-related cognitive impairment and dementia
X Fang, RF Crumpler, KN Thomas… - Physiology …, 2022 - akjournals.com
Cognitive impairment and dementia are significant health burdens worldwide. Aging,
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …
[HTML][HTML] The spontaneous immortalization probability of mammalian cell culture strains, as their proliferative capacity, correlates with species body mass, not longevity
M Perillo, A Punzo, C Caliceti, C Sell, A Lorenzini - biomedical journal, 2023 - Elsevier
Abstract Background The Peto's paradox consists in the observation that individuals from
long-lived and large animal species do not experience a higher cancer incidence, despite …
long-lived and large animal species do not experience a higher cancer incidence, despite …
Single-cell protein activity analysis reveals a novel subpopulation of chondrocytes and the corresponding key master regulator proteins associated with anti …
Z Guang, Z Min, L Jun-Tan, D Tian-Xu… - Frontiers in …, 2023 - frontiersin.org
Background Osteoarthritis (OA) is a prevalent senescence-related disease with substantial
joint pain, loss of joint function, and cartilage degeneration. Because of the paucity of single …
joint pain, loss of joint function, and cartilage degeneration. Because of the paucity of single …