There has been a long history of lesioning procedures to treat tremor associated with both
essential tremor (ET) and Parkinson's disease (PD). These include radiofrequency (RF) …

Ultrasound ablation techniques are minimally invasive alternatives to surgical resection and
have rapidly increased in use. The response of tissue to HIFU ablation differs based on the …

High quality tissue-mimicking phantoms (TMPs) have a critical role in the preclinical testing
of emerging modalities for diagnosis and therapy. TMPs capable of accurately mimicking …

Histotripsy has been previously applied to target various cranial locations in vitro through an
excised human skull. Recently, a transcranial magnetic resonance (MR)-guided histotripsy …

Focused ultrasound (FUS) thalamotomy is an emerging treatment for tremor-dominant
Parkinson's disease (PD). We report the first postmortem neuropathologic study of FUS …

Objectives No method is available to determine the non-perfused volume (NPV) repeatedly
during magnetic resonance–guided high-intensity focused ultrasound (MR-HIFU) ablations …

OBJECTIVE The ability to predict final lesion characteristics during magnetic resonance–
guided focused ultrasound (MRgFUS) thalamotomy for the treatment of essential tremor …

OBJECTIVE Outcomes after focused ultrasound ablation (FUSA) for essential tremor remain
heterogeneous, despite therapeutic promise. Clinical outcomes are directly related to the …

Objective To investigate the value of T2-weighted imaging (T2WI) and diffusion-weighted
imaging (DWI) in evaluating the therapeutic effect of high-intensity focused ultrasound …

There is a growing field of minimally and non‐invasive techniques that are being utilized to
cause localized thermal ablation and necrosis for the treatment of many diseases. Several …