Biological imaging of chemical bonds by stimulated Raman scattering microscopy
All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …
molecular vibration spectra in living cells and tissues. However, the transition from …
Instant diagnosis of gastroscopic biopsy via deep-learned single-shot femtosecond stimulated Raman histology
Gastroscopic biopsy provides the only effective method for gastric cancer diagnosis, but the
gold standard histopathology is time-consuming and incompatible with gastroscopy …
gold standard histopathology is time-consuming and incompatible with gastroscopy …
Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy
Conventional methods for intraoperative histopathologic diagnosis are labour-and time-
intensive, and may delay decision-making during brain-tumour surgery. Stimulated Raman …
intensive, and may delay decision-making during brain-tumour surgery. Stimulated Raman …
Raman spectroscopy: techniques and applications in the life sciences
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy
M Ji, DA Orringer, CW Freudiger… - Science translational …, 2013 - science.org
Surgery is an essential component in the treatment of brain tumors. However, delineating
tumor from normal brain remains a major challenge. We describe the use of stimulated …
tumor from normal brain remains a major challenge. We describe the use of stimulated …
Label-free DNA imaging in vivo with stimulated Raman scattering microscopy
Label-free DNA imaging is highly desirable in biology and medicine to perform live imaging
without affecting cell function and to obtain instant histological tissue examination during …
without affecting cell function and to obtain instant histological tissue examination during …
Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering
ABL1 tyrosine-kinase inhibitors (TKI) are front-line therapy for chronic myelogenous
leukaemia and are among the best-known examples of targeted cancer therapeutics …
leukaemia and are among the best-known examples of targeted cancer therapeutics …
Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy
Differentiating tumor from normal brain is a major barrier to achieving optimal outcome in
brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery …
brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery …
Coherent Raman scattering microscopy in biology and medicine
Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …
visualization and analysis of functional, endogenous biomolecules in living systems. When …