All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …

Gastroscopic biopsy provides the only effective method for gastric cancer diagnosis, but the
gold standard histopathology is time-consuming and incompatible with gastroscopy …

Conventional methods for intraoperative histopathologic diagnosis are labour-and time-
intensive, and may delay decision-making during brain-tumour surgery. Stimulated Raman …

Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Surgery is an essential component in the treatment of brain tumors. However, delineating
tumor from normal brain remains a major challenge. We describe the use of stimulated …

Label-free DNA imaging is highly desirable in biology and medicine to perform live imaging
without affecting cell function and to obtain instant histological tissue examination during …

ABL1 tyrosine-kinase inhibitors (TKI) are front-line therapy for chronic myelogenous
leukaemia and are among the best-known examples of targeted cancer therapeutics …

Differentiating tumor from normal brain is a major barrier to achieving optimal outcome in
brain tumor surgery. New imaging techniques for visualizing tumor margins during surgery …

Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …