" Omics" in pharmaceutical research: overview, applications, challenges, and future perspectives.
SK Yan, RH Liu, HZ Jin, XR Liu, J Ye… - Chinese journal of …, 2015 - europepmc.org
In the post-genomic era, biological studies are characterized by the rapid development and
wide application of a series of" omics" technologies, including genomics, proteomics …
wide application of a series of" omics" technologies, including genomics, proteomics …
Application of pharmacogenomics to vaccines
GA Poland, IG Ovsyannikova, RM Jacobson - Pharmacogenomics, 2009 - Taylor & Francis
The field of pharmacogenomics and pharmacogenetics provides a promising science base
for vaccine research and development. A broad range of phenotype/genotype data …
for vaccine research and development. A broad range of phenotype/genotype data …
[图书][B] Batch effects and noise in microarray experiments: sources and solutions
A Scherer - 2009 - Wiley Online Library
High-content, high-density long or short oligonucleotide microarrays for simultaneous
measurement of redundancy of RNA species are nowadays widely used for hypothesis …
measurement of redundancy of RNA species are nowadays widely used for hypothesis …
Gene expression profiling reveals potential prognostic biomarkers associated with the progression of heart failure
Background Heart failure (HF) is the most common cause of morbidity and mortality in
developed countries. Here, we identify biologically relevant transcripts that are significantly …
developed countries. Here, we identify biologically relevant transcripts that are significantly …
Update on myocarditis–what we know so far and where we may be heading
A Rroku, J Kottwitz, B Heidecker - European Heart Journal Acute …, 2021 - academic.oup.com
Myocarditis is defined as an inflammatory infiltration of the myocardium with associated
necrosis and/or degeneration, frequently resulting from different infectious or non-infectious …
necrosis and/or degeneration, frequently resulting from different infectious or non-infectious …
Big data: the next frontier for innovation in therapeutics and healthcare
Advancements in genomics and personalized medicine not only effect healthcare delivery
from patient and provider standpoints, but also reshape biomedical discovery. We are in the …
from patient and provider standpoints, but also reshape biomedical discovery. We are in the …
Transcriptomic biomarkers for the accurate diagnosis of myocarditis
Background—Lymphocytic myocarditis is a clinically important condition that is difficult to
diagnose and distinguish. We hypothesized that the transcriptome obtained from an …
diagnose and distinguish. We hypothesized that the transcriptome obtained from an …
Differential expression of oxidative stress and inflammation related genes in peripheral blood mononuclear cells in response to a low-calorie diet: a nutrigenomics …
AB Crujeiras, D Parra, FI Milagro… - OMICS A Journal of …, 2008 - liebertpub.com
Nutrigenomics is a new application of omics technologies in nutritional science.
Nutrigenomics aims to identify molecular markers of diet-related diseases and mechanisms …
Nutrigenomics aims to identify molecular markers of diet-related diseases and mechanisms …
The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences
B Heidecker, G Lamirault, EK Kasper… - European heart …, 2010 - academic.oup.com
Aims We sought to test the hypothesis that inherent biological factors contribute to gender
differences in disease pathophysiology of new-onset heart failure (HF), which can be …
differences in disease pathophysiology of new-onset heart failure (HF), which can be …
Integration of epigenetic mechanisms into non-genotoxic carcinogenicity hazard assessment: Focus on DNA methylation and histone modifications
D Desaulniers, P Vasseur, A Jacobs… - International Journal of …, 2021 - mdpi.com
Epigenetics involves a series of mechanisms that entail histone and DNA covalent
modifications and non-coding RNAs, and that collectively contribute to programing cell …
modifications and non-coding RNAs, and that collectively contribute to programing cell …