Clonal alterations in hematopoietic cells occur during aging and are often associated with
the establishment of a subclinical inflammatory environment. Several age-related conditions …

Major causes of morbidity and mortality in myeloproliferative neoplasms are represented by
arterial and venous complications, progression to myelofibrosis, and transformation to acute …

Budd-Chiari syndrome and non-cirrhotic non-tumoral portal vein thrombosis are 2 rare
disorders, with several similarities that are categorized under the term splanchnic vein …

Myeloproliferative neoplasms (MPNs), encompassing disorders like polycythemia vera (PV),
essential thrombocythemia (ET), and primary myelofibrosis (PMF), are characterized by …

Background Vascular activation is characterized by increased proinflammatory, pro
thrombotic, and proadhesive signaling. Several chronic and acute conditions, including Bcr …

What is the role of inflammation in Myeloproliferative Neoplasms? This is currently a topic of
much debate. In this review, we will discuss experimental results and basic concepts of …

Thrombosis is the main cause of morbidity and mortality in patients with JAK2V617F
myeloproliferative neoplasms. Recent studies have reported the presence of JAK2V617F in …

Primary myelofibrosis (PMF) is one of three myeloproliferative neoplasms (MPN) that are
morphologically and molecularly inter-related, the other two being polycythemia vera (PV) …

Primary myelofibrosis (PMF) is a Philadelphia chromosome negative myeloproliferative
neoplasm (MPN) with adverse prognosis and is associated with bone marrow fibrosis and …

Thromboembolic events are the main cause of mortality in BCR-ABL1-negative
myeloproliferative neoplasms (MPNs) but their underlying mechanisms are largely …