Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

Z Chen, R Tian, Z She, J Cai, H Li - Free Radical Biology and Medicine, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis

S Kumar, Q Duan, R Wu, EN Harris, Q Su - Advanced drug delivery reviews, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that encompasses a
spectrum of pathological conditions, ranging from simple steatosis (NAFL), nonalcoholic …

SGLT-2 inhibitors in NAFLD: expanding their role beyond diabetes and cardioprotection

T Androutsakos, N Nasiri-Ansari, AD Bakasis… - International journal of …, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is an 'umbrella'term, comprising a spectrum
ranging from benign, liver steatosis to non-alcoholic steatohepatitis, liver fibrosis and …

Chronic inflammation in non-alcoholic steatohepatitis: molecular mechanisms and therapeutic strategies

C Luci, M Bourinet, PS Leclère, R Anty… - Frontiers in …, 2020 - frontiersin.org
Non-Alcoholic Steatohepatitis (NASH) is the progressive form of Non-Alcoholic Fatty Liver
Disease (NAFLD), the main cause of chronic liver complications. The development of NASH …

An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease

TJ Kendall, M Jimenez-Ramos, F Turner… - Nature medicine, 2023 - nature.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the commonest cause
of chronic liver disease worldwide and represents an unmet precision medicine challenge …

Treating inflammation to combat non-alcoholic fatty liver disease

L Wiering, F Tacke - Journal of Endocrinology, 2023 - joe.bioscientifica.com
Non-alcoholic fatty liver disease (NAFLD) with its more progressive form non-alcoholic
steatohepatitis (NASH) has become the most common chronic liver disease, thereby …

[HTML][HTML] The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease

K Sawada, H Chung, S Softic, ME Moreno-Fernandez… - Cell Metabolism, 2023 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

CD4+ T cell activation and inflammation in NASH-related fibrosis

Y Zhou, H Zhang, Y Yao, X Zhang, Y Guan… - Frontiers in …, 2022 - frontiersin.org
Liver fibrosis is a common pathological feature of end stage liver failure, a severe life-
threatening disease worldwide. Nonalcoholic fatty liver disease (NAFLD), especially its more …

Nonalcoholic fatty liver disease: an emerging driver of hypertension

YC Zhao, GJ Zhao, Z Chen, ZG She, J Cai, H Li - Hypertension, 2020 - Am Heart Assoc
Hypertension, a multifactorial disorder resulting from the interplay between genetic
predisposition and environmental risk factors, affects≈ 30% of adults. Emerging evidence …

Liver steatosis, gut-liver axis, microbiome and environmental factors. A never-ending bidirectional cross-talk

A Di Ciaula, J Baj, G Garruti, G Celano… - Journal of clinical …, 2020 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …